在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

HOXB7 Antibody

  • 中文名稱:
    HOXB7兔多克隆抗體
  • 貨號:
    CSB-PA010667ESR1HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA010667ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA010667ESR1HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) HOXB7 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HOXB7
  • 別名:
    HOXB7 antibody; HOX2C antibody; Homeobox protein Hox-B7 antibody; Homeobox protein HHO.C1 antibody; Homeobox protein Hox-2C antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Homeobox protein Hox-B7 protein (1-120AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  • 基因功能參考文獻:
    1. hsa_circ_0074362 plays a crucial role in glioma progression by regulating the miR-1236-3p/HOXB7 pathway. PMID: 30388035
    2. miR-196b-5p inhibition led to significantly increased colorectal cancer cell migration/invasion and metastases formation in mice, whereas ectopic overexpression showed the opposite phenotype. Molecular profiling and target confirmation identified an interaction between miR-196b-5p and HOXB7 and GALNT5, which in turn regulated colorectal cancer cell migration PMID: 28533224
    3. The expression of HOXB7 was upregulated in osteosarcoma tissues and cells compared with paired adjacent nontumor bone tissues and osteoblastic cells using reverse transcriptionquantitative polymer chain reaction and western blotting. HOXB7 knockdown dramatically suppressed cell viability, proliferation, migration and epithelialmesenchymal transition. PMID: 28677742
    4. downregulation of HOXB7 inhibited proliferation, invasion, and tumorigenesis, partly through suppressing the PI3K/Akt signaling pathway in osteosarcoma cells. PMID: 27983923
    5. HOXB7 promotes HCC cell proliferation, migration, and invasion through the bFGF-induced MAPK/ERK pathway activation. It might be a novel prognostic factor in HCC and a promising therapeutic target for tumor metastasis and recurrence. PMID: 28454092
    6. Overexpression of HOXB7 was significantly correlated with poor prognosis of HCC. HOXB7 up-regulated c-Myc and Slug expression via the AKT pathway to promote the acquisition of stem-like properties and facilitate epithelial-mesenchymal transition of hepatoma cells, accelerating the malignant progression of HCC. PMID: 28646927
    7. MiR-376c-3p suppresses the fission, proliferation, migration and invasion and induces cell apoptosis of oral squamous cancer cells via targeting HOXB7. PMID: 28482289
    8. our results showed that increased expression of HOXB7 might play an important role in promoting GC proliferation, migration and invasion by inducing both AKT and MAPK pathways, thus resulting in progression of, and poor prognosis in GC patients. PMID: 27901487
    9. the overexpression of HOXB7 in HSC-4 and KB/VCR cells reduces the sensitivity of the cells to chemo-radiotherapy-induced apoptosis and promotes oral cancer cell migration and invasion via upregulation of TGFbeta2. PMID: 27834359
    10. These findings suggest that hoxb7 and hoxb9 proteins might play a role in salivary gland tumourigenesis, but in contrast to the reported for other human cancers, they were not significant prognostic determinants in the sample studied. PMID: 26991799
    11. These results suggested that HOXB7 stimulates ERK1/2 phosphorylation and provided evidence that HOXB7, besides its role in transcriptional regulation, also promotes cell motility and invasiveness. PMID: 28912272
    12. The study suggests that HOXB7 has an oncogenic role in gastric cancer, which might be related to the modulation of Akt/PTEN activity to induce cell migration/invasion and anti-apoptotic effects. PMID: 26968988
    13. Suggest that simultaneous targeting of key regulatory miRNA miR-222 and HOXB7 may be a useful strategy for prevention of colorectal cancer metastasis. PMID: 27855613
    14. HOXB7 expression was significantly associated with larger tumor size and higher rate of biliary invasion in hepatocellular carcinoma. PMID: 27272787
    15. HOXB7 is generally overexpressed in gastric cancer, is associated with patient clinical characteristics, and specifically promotes gastric cancer cell malignant biological properties PMID: 26307396
    16. MiR-337 targets HOXB7 and effects significant suppression of pancreatic ductal adenocarcinoma (PDAC) cell proliferation and invasion. PMID: 25183455
    17. Results point out the complex interplay between the DSB DNA repair activity and the homeoproteins HoxB7 and Cdx2 in colon cancer cells. PMID: 26902420
    18. HOXB7 protein expression level is downregulated following siRNA transfection and downregulation of HOXB7 gene expression effectively inhibits MCF-7 cell proliferation. PMID: 26135503
    19. Myelomeningocele is significantly associated with HOXB7 hypomethylation. PMID: 25565354
    20. HOXB7 Is an ERalpha Cofactor in the Activation of HER2 and Multiple ER Target Genes Leading to Endocrine Resistance PMID: 26180042
    21. HOXB7 could promote cancer cell proliferation and might be an independent prognostic factor for patients with esophageal squamous cell carcinoma. PMID: 26076456
    22. Study reports >1,500 chromatin binding sites in the genome of a breast cancer cell line overexpressing HOXB7 and identifies some potential direct targets that are located nearby. PMID: 26014856
    23. Results demonstrate HOXB7 as a master factor driving progenitors behavior lifetime, providing a better understanding of bone senescence and leading to an optimization of MSC performance. PMID: 25428821
    24. HoxB7 is associated with tumor metastasis in patients with lung adenocarcinoma and HoxB7 may be implicated in promoting the development of lung adenocarcinoma through activation of the TGF-beta/SMAD3 signaling. PMID: 26403398
    25. our results suggest that HOXB7 promotes tumor progression in a cell-autonomous and non-cell-autonomous manner through activation of the TGFbeta signaling pathway. PMID: 25542862
    26. Results suggest that p53-regulated TUG1 is a growth regulator, which acts in part through control of HOXB7 in non-small cell lung cancer. PMID: 24853421
    27. HOXB7 was over-expressed and miR-337 was minimally expressed in pancreatic ductal adenocarcinoma PMID: 24641834
    28. HOXB7 mRNA is overexpressed in pancreatic ductal adenocarcinomas and its knockdown induces cell cycle arrest and apoptosis. PMID: 24088503
    29. HOXB7 promotes LAC progression by enhancing proliferation and metastasis. PMID: 22911672
    30. MicroRNA-196b regulates the HOXB7-VEGF axis in cervical cancer. PMID: 23861821
    31. findings suggest the disruption of the HOXB7/PBX2 complexes, miR-221&222 inhibition or even better their combination, as innovative therapeutic approaches PMID: 23400877
    32. HOXB7 is frequently overexpressed in pancreatic adenocarcinoma, specifically promotes invasive phenotype, and is associated with lymph node metastasis and worse survival outcome. PMID: 22914903
    33. Measuring IGF2BP3, HOXB7 and NEK2 mRNA levels by RT-PCR in addition to cytology has the potential to improve detection of malignant biliary disorders from brush cytology specimens. PMID: 22879911
    34. a novel mechanism whereby polyADP-ribosylation regulates transcriptional activities of HOX proteins such as HOXB7 and HOXA7 PMID: 22844406
    35. the absence of HoxB7 leads to inefficient viral progeny production, as HAdV5 gene expression is highly regulated by HoxB7-mediated activation of various adenoviral promoters. PMID: 22553335
    36. The current study demonstrates that the expression of HOXB7 is an independent prognostic marker for oral squamous cell carcinoma. PMID: 22239410
    37. Up-regulation of EGFR occurs through direct binding of HOXB7 to the EGFR promoter, enhancing transcriptional activity. PMID: 21690342
    38. Data indicate that HOXB7 and related HOX genes are upregulated in plasma cells of specific subsets of multiple myeloma patients lacking major immunoglobulin heavy chain locus translocations, irrespective of hyperdiploidy or other cytogenetic lesions. PMID: 21953534
    39. Here, we showed that PI3K/AKT and MAPK pathways were activated because p-ERK, p-AKT and p-GSK3-beta were upregulated by HOXB7. PMID: 21474578
    40. confirmed that HOXB7 overexpression by multiple myeloma (MM) cells stimulated tumor growth, increased MM-associated angiogenesis and the expression of pro-angiogenic genes by microarray analysis PMID: 21183939
    41. Strongly reduced expression of the microRNA miR-196a in melanoma cells compared to healthy melanocytes leads to enhanced HOX-B7 mRNA and protein levels, which subsequently raise Ets-1 activity by inducing basic fibroblast growth factor (bFGF). PMID: 20480203
    42. Differential expression of HOXB7 gene in multiple myeloma and extramedullary multiple myeloma patients PMID: 19878270
    43. HOXB7 may contribute to oral carcinogenesis by increasing tumor cell proliferation PMID: 19956843
    44. Identification of transcription factors that regulate HOXB7 expression. PMID: 12697323
    45. HOXB7 is expressed from primordial and early primary stage follicles through to germinal vesicle (GV) oocytes. PMID: 16597639
    46. Homeobox B7 (HoxB7) mRNA is overexpressed in biliary cancer cell lines and possibly involved in the pathogenesis of bile duct cancer. PMID: 16673309
    47. HOXB7 promotes tumor invasion through activation of Ras/Rho pathway by up-regulating bFGF. HOXB7 overexpression causes epithelial-mesenchymal transition in epithelial cells, accompanied by aggressive properties of tumorigenicity, migration, & invasion. PMID: 17018609
    48. thalidomide inhibits the RA-induced HOXB7 expression in glioblastoma cells PMID: 17514648

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Antp homeobox family
  • 數據庫鏈接:

    HGNC: 5118

    OMIM: 142962

    KEGG: hsa:3217

    STRING: 9606.ENSP00000239165

    UniGene: Hs.436181



主站蜘蛛池模板: 老子影院午夜伦手机不四虎卡 | 精品久久久久久无码免费| 亚洲欧洲日产韩国无码| 国产午夜高清高清在线观看| 国产成人精品av| 性做久久久久久| 久久久综合九色综合88| 国产无遮挡又黄又爽奶头| 亚洲线精品一区二区三区影音先锋| 欧美国产精品日韩在线| 欧美精品亚洲精品日韩专区va| 精品国内自产拍在线观看| 亚洲成av人片在线观看无| 欧美老妇大p毛茸茸| 欲求不满邻居的爆乳在线播放| 亚洲va久久久噜噜噜久久无码| 插一插射一射视频| 国产精品久久无码一区二区三区网| 最新国产精品拍自在线观看| 欧美人与动性行为视频| 午夜成人理论无码电影在线播放 | 久久久久久无码午夜精品直播| 亚洲欧洲免费无码| 尤物yw午夜国产精品大臿蕉| 国产成人午夜福利免费无码r| 亚洲精品欧美二区三区中文字幕| 人人妻人人澡人人爽国产一区 | 精品久久无码中文字幕| 精品一区二区三区东京热| 学生妹无套内射正在播放 | 高潮爽死抽搐白浆gif视频| 最新亚洲人成无码网站| 国内精品伊人久久久久777| 亚洲va在线va天堂xx xx| 97免费人妻在线视频| 欧美人妻一区二区三区| 免费无码一区二区三区蜜桃大| 国产精品人成电影在线观看| 亚洲 欧美 激情 小说 另类| 人妻熟人中文字幕一区二区| 高潮内射双龙视频|