在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HOOK2 Antibody

HOOK2 Antibody

  • 中文名稱：
    HOOK2兔多克隆抗體
  • 貨號：
    CSB-PA839313ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: HOOK2 antibody at 4.11 μg/ml
      Lane 1: Mouse small intestine tissue
      Lane 2: A431 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 83 kDa
      Observed band size: 83 kDa
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA839313ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA839313ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) HOOK2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HOOK2
  • 別名：
    HOOK2 antibody; Protein Hook homolog 2 antibody; h-hook2 antibody; hHK2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Protein Hook homolog 2 protein (440-719AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Contributes to the establishment and maintenance of centrosome function. May function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell.
  • 基因功能參考文獻：
    1. We first demonstrate that Hook2 is essential for the polarized Golgi re-orientation towards the migration front. Depletion of Hook2 results in a decrease of PAR6alpha at the centrosome during cell migration, while overexpression of Hook2 in cells induced the formation of aggresomes with the recruitment of PAR6alpha, aPKC and PAR3 PMID: 27624926
    2. differential methylation profile of the HOOK2 gene in individuals with T2D and obesity might be related to the attendant T2D, but further studies are required to identify the potential role of HOOK2 gene in T2D disease PMID: 29228058
    3. Hook2 localizes at the Golgi apparatus and centrosome/basal body, a strategic partitioning for ciliogenesis. Hook2 interacts with PCM1. PMID: 21998199
    4. Results identify Hook2, a linker protein that is essential for regulation of the microtubule network at the centrosome, as a binding partner of CENP-F. PMID: 19793914
    5. Hook2 contributes to the establishment and maintenance of the pericentrosomal localization of aggresomes by promoting the microtubule-based delivery of protein aggregates to pericentriolar aggresomes. PMID: 17540036

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cytoplasm, cytoskeleton. Golgi apparatus, trans-Golgi network.
  • 蛋白家族：
    Hook family
  • 數據庫鏈接：

    HGNC: 19885

    OMIM: 607824

    KEGG: hsa:29911

    STRING: 9606.ENSP00000380785

    UniGene: Hs.30792



主站蜘蛛池模板： 中文无码av在线亚洲电影| 久久久久国产精品人妻aⅴ毛片 | 精品亚洲欧美自拍| 日韩精品专区在线影院重磅| 欧美群妇大交群| 欧美疯狂性受xxxxx另类| 三上悠亚精品一区二区久久| 国精品人妻无码一区二区三区蜜柚| 男女猛烈无遮挡免费视频在线观看| 欧美成人猛片aaaaaaa| 亚洲色18禁成人网站www| 一区二区伊人久久大杳蕉 | 国产在线视频一区二区三区| 九九久久精品国产av片国产| 亚洲中文在线播放一区| 久久99亚洲精品久久久久| 奶头好大狂揉60分钟视频 | 欧洲人妻丰满av无码久久不卡| 亚洲欧美色一区二区三区| 亚洲中文字幕永久在线不卡| 国产肉丝袜在线观看| 别揉我奶头~嗯~啊~一区二区三区| 国产成人免费无码av在线播放| 人人妻人人澡人人爽| 丰满少妇呻吟高潮经历| 国产男女猛烈无遮挡免费视频| 欧美成人家庭影院| 五月激激激综合网亚洲| 久久久国产乱子伦精品| 亚洲国产一区二区三区波多野结衣| 97久久久久人妻精品区一| 亚洲一区在线日韩在线尤物| 久久久精品人妻一区二区三区gv| 免费裸体无遮挡黄网站免费看| 豆国产96在线 | 亚洲| 欧美国产激情一区二区在线| 国产欧美日韩另类精彩视频| 青青草原综合久久大伊人| 国产又爽又黄无码无遮挡在线观看| 无码精品日韩专区| 国产在线视频一区二区三区|