在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HOOK1 Antibody

HOOK1 Antibody

  • 中文名稱：
    HOOK1兔多克隆抗體
  • 貨號：
    CSB-PA010640GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    A930033L17Rik antibody; Abnormal spermatozoon head shape antibody; azh antibody; h-hook1 antibody; hHK1 antibody; HK1 antibody; HOOK 1 antibody; Hook homolog 1 (Drosophila) antibody; Hook1 antibody; HOOK1_HUMAN antibody; MGC10642 antibody; OTTHUMP00000010548 antibody; OTTMUSP00000008480 antibody; Protein Hook homolog 1 antibody; RP23-80B16.4 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human HOOK1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell. Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton.
  • 基因功能參考文獻：
    1. Hook1 knockdown promoted epithelial-mesenchymal transition and attenuated the sensitivity of hepatocellular carcinoma cells to doxorubicin. In summary, our results indicate that downregulation of Hook1 plays a pivotal role in hepatocellular carcinoma progression via epithelial-mesenchymal transition. Hook1 may be used as a novel marker and therapeutic molecular target in hepatocellular carcinoma PMID: 28718370
    2. Single-molecule motility assays using total internal reflection fluorescence microscopy indicate that both Hook1 and Hook3 effectively activate cytoplasmic dynein, inducing longer run lengths and higher velocities than the previously characterized dynein activator bicaudal D2 (BICD2). PMID: 27365401
    3. SHP2 positively regulates TGFbeta1-induced epithelial-mesenchymal transition modulated by its novel interacting protein Hook1. PMID: 25331952
    4. Hook1, a microtubule- and cargo-tethering protein, recognized the cytoplasmic tail of CD147 to help sort it and CD98 into Rab22a-dependent tubules associated with recycling. PMID: 23589492
    5. novel interactions between the microtubule-binding Hook1 and the large family of Rab GTPases also suggest a link between CLN3 function, microtubule cytoskeleton and endocytic membrane trafficking PMID: 15471887
    6. These data suggest that the FTS/Hook/FHIP complex functions to promote vesicle trafficking and/or fusion via the homotypic vacuolar protein sorting complex. PMID: 18799622

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Hook family
  • 數據庫鏈接：

    HGNC: 19884

    OMIM: 607820

    KEGG: hsa:51361

    STRING: 9606.ENSP00000360252

    UniGene: Hs.378836



主站蜘蛛池模板： 亚洲国产最大av| av第一福利网站| 纯爱无遮挡h肉动漫在线播放| 成人aaa片一区国产精品| 亚洲精品一区中文字幕乱码| 2019久久视频这里有精品15| 无码伊人66久久大杳蕉网站谷歌| 国产边打电话边被躁视频| 99久久精品日本一区二区免费 | 2020最新无码国产在线观看| 亚洲 制服 丝袜 无码 在线| 国产精品无码无片在线观看| 国产午夜福利精品一区二区三区| 欧美兽交xxxx×视频| 国产 成人 综合 亚洲 网站| 国产精品99爱免费视频| 狠狠躁天天躁中文字幕无码| 色一情一区二区三区四区| 亚洲久热中文字幕在线| 亚洲日本va中文字幕人妖| 国内精品久久久久久久小说| 18禁白丝喷水视频www视频| 伊人久久大香线蕉亚洲| 免费国产成人高清在线观看网站| 国产成人无码激情视频| 国产成人无码av一区二区在线观看 | 国产无遮挡18禁无码网站免费| 人妻无码久久精品人妻| 自偷自拍亚洲综合精品| 欧美伦费免费全部午夜最新| 无码一区二区三区在线| 98国产精品综合一区二区三区| 亚洲高清有码中文字| 一边摸一边叫床一边爽av| 一本大道熟女人妻中文字幕在线| 99re热视频这里只精品| 国产无套粉嫩白浆在线| 999精品无码a片在线1级| 亚洲日韩成人无码| 国产成人 综合 亚洲欧洲| 狂野欧美激情性xxxx按摩|