在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

HNRNPF Antibody

  • 中文名稱:
    HNRNPF兔多克隆抗體
  • 貨號:
    CSB-PA571130
  • 規(guī)格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from HepG2 cells, using hnRNP F antibody.
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) HNRNPF Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HNRNPF
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from N-terminal of Human hnRNP F.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.
  • 基因功能參考文獻:
    1. hnRNP H/F are important for maintenance and differentiation of embryonic stem cells and that this at least in part reflects a switch in TCF3 alternative splicing that leads to repression of CDH1/E-cadherin. PMID: 30115631
    2. Results from a study on gene expression variability markers in early-stage human embryos shows that HNRNPF is a putative marker for the 3-day, 8-cell embryo stage. PMID: 26288249
    3. heterogeneous nuclear ribonucleoprotein F (hnRNPF) regulates G-quadruplex-associated alternative splicing across the transcriptome. PMID: 29269483
    4. Simulation results demonstrate that the RNA binding domain qRRM2 of hnRNP F binds strongly with G-tract RNA, but any mutation of the G-tract leads to a drastic reduction of the binding free energy. PMID: 29050934
    5. Human T2D kidneys exhibited more RPTC apoptosis and lower expression of hnRNP F, SIRTUIN-1, and FOXO3alpha than nondiabetic kidneys. PMID: 28424160
    6. hnRNP F is a co-factor in a subset of tristetraprolin/BRF1/BRF2-mediated mRNA decay. PMID: 24978456
    7. this result suggests that hnRNP F directs formation of the exon 4 minus variant of ENOX2. PMID: 21625959
    8. The study shows solution structures of the three quasi-RNA-recognition motifs of heterogeneous nuclear ribonucleoprotein F in complex with G-tract RNA. PMID: 20526337
    9. heterogeneous ribonucleoprotein F is involved in the regulation of cell proliferation via the mammalian target of rapamycin/S6 kinase 2 pathway PMID: 20308064
    10. Results suggest that hnRNP H and F are nuclear shuttling proteins whose posttranslational modifications may alter interaction with transportin 1, nuclear localization, and hence function. PMID: 20308327
    11. high levels of hnRNP F are present in premalignant and malignant stages of colorectal cancer, reflecting a role for this protein early in colorectal tumorigenesis PMID: 16424007
    12. The solution structure of the three quasi RNA recognition motifs of hnRNP F and identification of the residues that are important for the interaction with the Bcl-x RNA. PMID: 16885237
    13. hnRNPH and F regulate DM20 splicing by recruiting U1snRNP and hnRNPH plays a primary role in DM20 splice site selection in vivo PMID: 19244236
    14. Shows that hnRNPF regulates the 3' end cleavage reaction. PMID: 11158309

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus, nucleoplasm.
  • 組織特異性:
    Expressed ubiquitously.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 5039

    OMIM: 601037

    KEGG: hsa:3185

    STRING: 9606.ENSP00000338477

    UniGene: Hs.712955



主站蜘蛛池模板: 欧洲亚洲1卡二卡三卡2021| 欧美成人片在线观看| 四虎免费大片aⅴ入口| 国产欧美熟妇另类久久久| 久久www成人_看片免费不卡| 国产成人无码免费视频麻豆| 亚洲 制服 丝袜 无码 在线| 亚洲国产欧美在线人成| 国产精品亚洲αv天堂无码| 色婷婷久久久swag精品| 天无日天天射天天视| 国产成+人欧美+综合在线观看| 日本中文字幕乱码免费| 色拍拍欧美视频在线看| 免费人成年激情视频在线观看| 天天澡天天揉揉av无码| 久久99精品久久久久久蜜芽 | 免费人妻av无码专区| 国产成人综合欧美精品久久| 狠人干练合综合网| 久久久肥妇熟女ⅹxxx毛片| 男人和女人在床的app| 夜爽8888视频在线观看| 中文字幕人妻a片免费看| 国产精品 中文字幕 亚洲 欧美| 毛片内射久久久一区| 97视频在线观看播放| 男人天堂2018亚洲男人天堂| 日日日日做夜夜夜夜无码| 午夜亚洲福利在线老司机| 午夜无码乱码在线观看| 亚在线第一国产州精品99| 亚洲国产精品隔壁老王| 乌克兰少妇videos高潮| 国产免费一区二区视频| 久久66热人妻偷产精品| 免费无码又爽又黄又刺激网站| 无码av高潮抽搐流白浆| 97超碰精品成人国产| 国产av影片麻豆精品传媒| 无码人妻一区二区三区av|