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HIPK4 Antibody

  • 中文名稱:
    HIPK4兔多克隆抗體
  • 貨號(hào):
    CSB-PA999254
  • 規(guī)格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from HUVEC cells, using HIPK4 antibody.
    • Immunohistochemistry analysis of paraffin-embedded human testis tissue using HIPK4 antibody.
    • Immunofluorescence analysis of A549 cells, using HIPK4 antibody.
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) HIPK4 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from internal of Human HIPK4.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC,IF
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:100
    IF 1:100-1:500
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter. May act as a corepressor of transcription factors (Potential).
  • 基因功能參考文獻(xiàn):
    1. loss of HIPK4 expression improves early skin epithelial differentiation accompanied by an increase in K8 and K18 expression, and improves late keratinocyte differentiation with an increase of epidermal identity PMID: 28966120
    2. Analysis of these mutants revealed that HIPK1, HIPK2 and HIPK3 but not HIPK4 are capable of autophosphorylating on other tyrosines PMID: 25630557
    3. homeodomain interacting protein kinase 4 could phosphorylate human p53 protein at serine 9, both in vitro and in vivo PMID: 18022393
  • 亞細(xì)胞定位:
    Cytoplasm.
  • 蛋白家族:
    Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 19007

    OMIM: 611712

    KEGG: hsa:147746

    STRING: 9606.ENSP00000291823

    UniGene: Hs.79363



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