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  4. HEXIM2 Antibody, HRP conjugated

HEXIM2 Antibody, HRP conjugated

  • 中文名稱：
    HEXIM2兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA010319LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) HEXIM2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HEXIM2
  • 別名：
    Hexamethylene bis-acetamide-inducible protein 2 antibody; Hexamthylene bis-acetamide inducible 2 antibody; HEXI2_HUMAN antibody; hexim 2 antibody; HEXIM2 antibody; L3 antibody; Protein HEXIM2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Protein HEXIM2 protein (1-286AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
  • 基因功能參考文獻：
    1. HEXIM2 can functionally and quantitatively compensate for the loss of HEXIM1 PMID: 15713661
    2. utilization of HEXIM1 or HEXIM2 to bind and inhibit P-TEFb can be differentially regulated in vivo. PMID: 15713662
    3. Positive transcription elongation factor b regulates eukaryotic gene expression at the level of elongation and is controlled by the reversible association with HEXIM2. PMID: 15965233
    4. The tripartite protein-RNA complex formation between Hexim, Cyclin T and 7SK snRNA, was analyzed. PMID: 19883659
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    HEXIM family
  • 組織特異性：
    Ubiquitously expressed with higher expression in testis. HEXIM1 and HEXIM2 are differentially expressed.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 28591

    OMIM: 615695

    KEGG: hsa:124790

    STRING: 9606.ENSP00000302276

    UniGene: Hs.56382



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