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HCFC1R1 Antibody, FITC conjugated

  • 中文名稱：
    HCFC1R1兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA865161LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) HCFC1R1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HCFC1R1
  • 別名：
    HCF 1 beta propeller interacting protein antibody; HCF-1 beta-propeller-interacting protein antibody; HCF1 beta propeller interacting protein antibody; HCFC1R1 antibody; Host cell factor C1 regulator 1 (XPO1 dependent) antibody; Host cell factor C1 regulator 1 antibody; HPIP antibody; HPIP_HUMAN antibody; Inhibitor of four 2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Host cell factor C1 regulator 1 protein (1-119AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus.
  • 基因功能參考文獻(xiàn)：
    1. HPIP overexpression is an independent predictor of platinum-based chemotherapy resistance in epithelial ovarian neoplasms. PMID: 27818289
    2. HPIP promotes thyroid cancer cell growth, migration and epithelial mesenchymal transformation through activating PI3K/AKT signaling pathway. PMID: 26463629
    3. HPIP is upregulated in colorectal cancer and regulates colorectal cancer cell proliferation, apoptosis and invasion PMID: 25800793
    4. HPIP regulates HCF-1 activity by modulating its subcellular localization PMID: 12235138
  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner.
  • 組織特異性：
    Widely expressed.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 21198

    KEGG: hsa:54985

    UniGene: Hs.423103



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