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HBZ Antibody

Rare Species
  • 中文名稱:
    HBZ兔多克隆抗體
  • 貨號:
    CSB-PA314490XA01HQG
  • 規(guī)格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes: HBZ Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 29 kDa
      Observed band size: 36 kDa
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    HBZ
  • 別名:
    HTLV-1 basic zipper factor (HBZ) HBZ
  • 反應種屬:
    Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1)
  • 免疫原:
    Recombinant Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1) HBZ protein (1-209aa)
  • 免疫原種屬:
    Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Affinity-chromatography
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Enhances viral infectivity and persistence, and facilitates proliferation of HTLV-1-infected lymphocytes. Mechanistically, inhibits Tax-mediated viral replication and NF-kappa-B activation. Plays a role in allowing infected T-cells to escape the cytotoxic T-lymphocyte response by maintaining low levels of viral protein production. Inhibits also host EP300 histone acetyltransferase (HAT) activity, reducing levels of acetylated histone H3 at 'Lys-18' (H3K18ac) in infected cells. Contributes to the accumulation of chromosomal abnormalities by inhibiting double-stranded DNA breaks (DSB) repair through the NHEJ pathway. Participates in the modulation of host immune response at multiple levels contributing to abnormal interferon signaling and viral pathogenesis.
  • 亞細胞定位:
    Host nucleus.
  • 蛋白家族:
    HTLV-1 HBZ protein family


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