HAAO Antibody

說明書

產品詳情

Uniprot No.：

P46952
基因名：

HAAO
別名：

3 HAO antibody; 3 hydroxyanthranilate 3 4 dioxygenase antibody; 3 hydroxyanthranilate dioxygenase antibody; 3 hydroxyanthranilate oxygenase antibody; 3 hydroxyanthranilic acid dioxygenase antibody; 3-HAO antibody; 3-hydroxyanthranilate 3,4-dioxygenase antibody; 3-hydroxyanthranilate oxygenase antibody; 3-hydroxyanthranilic acid dioxygenase antibody; 3HAO_HUMAN antibody; haao antibody; HAD antibody; HAO antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human HAAO
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
基因功能參考文獻：
1. Here, the first crystal structure of human 3-HAO with the native iron bound in its active site is presented, together with an additional structure with zinc (a known inhibitor of human 3-HAO) bound in the active site. PMID: 28375145
2. Methylation status of CIDEA, HAAO and RXFP3 had significant association with microsatellite instability in endometrial tumors. PMID: 20211485
3. GTF2A1 alone, or GTF2A1 plus HAAO are excellent candidate biomarkers for detecting Ovarian cancer PMID: 19724865
亞細胞定位：

Cytoplasm, cytosol.
蛋白家族：

3-HAO family
數據庫鏈接：

HGNC: 4796

OMIM: 604521

KEGG: hsa:23498

STRING: 9606.ENSP00000294973

UniGene: Hs.368805

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