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H2AFJ Antibody

  • 中文名稱：
    H2AFJ兔多克隆抗體
  • 貨號：
    CSB-PA010094DA01HU
  • 規格：
    ￥880
  • 圖片：
    • IHC image of CSB-PA010094DA01HU diluted at 1:50 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) H2AFJ Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    H2AFJ antibody; Histone H2A.J antibody; H2a/j antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Histone H2A.J protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
  • 基因功能參考文獻：
    1. Histone variant H2A.J (H2A.J) accumulates in senescent fibroblasts with DNA damage. PMID: 28489069
    2. The antimicrobial protein buforin I results from proteolytic cleavage of the histone protein H2A in the stomach. PMID: 21178486
    3. In this paper, the authors identified and cloned the H2AFJ gene on chr 12 and used it as a control for studying two macroH2A genes. PMID: 11331621
  • 亞細胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    Histone H2A family
  • 數據庫鏈接：

    HGNC: 14456

    KEGG: hsa:55766

    STRING: 9606.ENSP00000373730

    UniGene: Hs.524280



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