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  4. Gsta1 Antibody, Biotin conjugated

Gsta1 Antibody, Biotin conjugated

  • 中文名稱：
    Gsta1兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA009970HD01MO
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Mus musculus (Mouse) Gsta1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    Gsta1
  • 別名：
    Gsta1 antibody; Gsta antibody; Gstya antibody; Glutathione S-transferase A1 antibody; EC 2.5.1.18 antibody; 13-hydroperoxyoctadecadienoate peroxidase antibody; EC 1.11.1.- antibody; Androst-5-ene-3,17-dione isomerase antibody; EC 5.3.3.- antibody; GST class-alpha member 1 antibody; Glutathione S-transferase Ya antibody; Glutathione S-transferase Ya1) [Cleaved into: Glutathione S-transferase A1 antibody; N-terminally processed] antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Mouse
  • 免疫原：
    Recombinant Mouse Glutathione S-transferase A1 protein (2-223AA)
  • 免疫原種屬：
    Mus musculus (Mouse)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene-3,17-dione and may therefore play an important role in hormone biosynthesis. Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid.
  • 基因功能參考文獻：
    1. GSTA1 can be detected at the early stage of low concentration ethanol exposure and that GSTA1 is more sensitive and reliable marker in ethanol-induced hepatic injury. PMID: 27198676
    2. results suggest that GSTA1 can be detected at low concentrations during the early stages of acute hepatic injury and that GSTA1 is a more sensitive and more accurate indicator than ALT PMID: 24964013
    3. Report increased GSTA1 in airways of asthmatic mice. PMID: 23647087
    4. mitochondrial Gsta1 is induced under oxidative stress PMID: 12020353
    5. Exceptional activity of murine glutathione transferase A1-1 against (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene-induced DNA damage in stably transfected cells PMID: 12557262
    6. This is the first demonstration that heavy metals (mercury, lead and copper) regulate the expression of Gst ya gene through a transcriptional mechanism. PMID: 16243960
    7. Analysis of the expressed luciferase activity indicated that MMA activated the promoter 2.6-fold. MMA (from 1 to 30 mM) dose-dependently increased the promoter activity, which reached a plateau between 6 and 12 hrs. PMID: 19029078
    8. Essential roles of ERKs and p38K in up-regulation of GST A1 expression by Maotai content in human hepatoma cell line Hep3B.It is widely accepted that the consumption of alcohol may lead to hepatic injuries such as hepatic fibrosis and cirrhosis. PMID: 16786188

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  • 蛋白家族：
    GST superfamily, Alpha family
  • 數據庫鏈接：


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