在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GYPC Antibody

  • 中文名稱:
    GYPC兔多克隆抗體
  • 貨號:
    CSB-PA180065
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA180065(GYPC Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA180065(GYPC Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    GYPC
  • 別名:
    GYPC; GLPC; GPC; Glycophorin-C; Glycoconnectin; Glycophorin-D; GPD; Glycoprotein beta; PAS-2'; Sialoglycoprotein D; CD antigen CD236
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Fusion protein of Human GYPC
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    IHC 1:100-1:300
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells.
  • 基因功能參考文獻:
    1. The authors set out to understand the similarities and differences among the GYPC deletion alleles Yus and Gerbich by positional PCR sequence analysis to identify the breakpoints. They developed a set of diagnostic PCRs that can be used to classify both Yus and Gerbich phenotypic variants on the basis of their nucleotide deletion. The Yus phenotype was defined by 4 different breakpoints and the Ger PMID: 28272739
    2. Plasmodium falciparum STEVOR functions as an erythrocyte-binding protein that recognizes Glycophorin C (GPC) on the red blood cell (RBC) surface and that its binding correlates with the level of GPC on the RBC surface. PMID: 25011110
    3. Rosetting assays using CD236R knockdown normocytes derived from hematopoietic stem cells further supports the role of glycophorin C as a receptor in P vivax rosette formation. PMID: 24652986
    4. Precise definition of the binding site for the EBA-140 ligand on glycophorin C may be important with respect to human erythrocyte invasion inhibition strategies based on a receptor. PMID: 24379273
    5. Glycophorin C delta (exon3) is not associated with protection against severe anaemia in Papua New Guinea. PMID: 21061946
    6. The Gerbich blood group system PMID: 20932076
    7. The molecular evolution of GYPC among the Hominoidea (Greater and Lesser Apes) and the pattern of polymorphism at the locus in a global human sample, were examined. PMID: 19679754
    8. Recombinant Ge2, Ge3 & Ge4 antigens were cloned, expressed and purified. Yus and Ge mutants behaved in SDS-PAGE similarly to normal GPC forms with diffuse glycosylation. PMID: 12058555
    9. Data show that the receptor for Plasmodium falciparum erythrocyte-binding antigen 140 (EBA140) is glycophorin C (GYPC) and that this interaction mediates a principal P. falciparum invasion pathway into human erythrocytes. PMID: 12469115
    10. Glycophorin C is identified as the receptor for PfEBP-2, the erythrocyte binding ligand of Plasmodium falciparum, and the binding domain on GPC is determined to be amino acid residues 14 through 22 within exon 2. PMID: 12576308
    11. Neither mutation was associated with altered susceptibility to asymptomatic Plasmodium falciparum or P. vivax infection. Contribution of these erythrocyte polymorphisms to susceptibility to clinical malaria morbidity requires further study. PMID: 14695625
    12. A high GYPC gene expression is associated with an unfavorable outcome, in contrast, a high TRIP3 gene expression is associated with a favorable outcome in childhood ALL. PMID: 19149918

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type III membrane protein. Note=Linked to the membrane via band 4.1.
  • 蛋白家族:
    Glycophorin-C family
  • 組織特異性:
    Glycophorin-C is expressed in erythrocytes. Glycophorin-D and IsoGPC are ubiquitously expressed.
  • 數據庫鏈接:

    HGNC: 4704

    OMIM: 110750

    KEGG: hsa:2995

    STRING: 9606.ENSP00000259254

    UniGene: Hs.59138



主站蜘蛛池模板: 又硬又粗又大一区二区三区视频| 精品一区二区三区在线播放视频| 极品少妇小泬50pthepon| 女子spa高潮呻吟抽搐| 欧美亅性猛交内射| 激情综合婷婷丁香五月情| 中文字幕久热精品视频在线| av老司机亚洲精品天堂| 久久精品人妻一区二区三区| 欧美色偷偷亚洲天堂bt| 国产青榴视频在线观看| 永久黄网站色视频免费| 国产丝袜无码一区二区视频| 未满十八18禁止午夜免费网站| 国产精品无码久久久久久| 精品欧美乱码久久久久久1区2区| 国产情侣草莓视频在线| 亚洲综合激情五月丁香六月| 黑人巨大精品欧美一区二区| 激情五月色综合国产精品| 成人啪精品视频网站午夜| 国产内射爽爽大片| 和岳每晚弄的高潮嗷嗷叫视频 | 国产乱人伦av在线无码| 黑人上司粗大拔不出来电影| 亚洲午夜精品a片一区二区app| 免费人成激情视频在线观看冫| 亚洲人成精品久久久久| 又大又粗又爽又黄的少妇毛片| 国产亚洲精品第一综合麻豆 | 欧美性猛交xxxx乱大交3| 国产美女被遭强高潮免费网站| 久久精品成人免费国产片小草| 五十路丰满中年熟女中出| 天天拍天天看天天做| 亚洲精品国产综合麻豆久久99| 亚洲熟妇av综合网五月| 吃奶呻吟打开双腿做受动态图| 男男gv白嫩小受gv在线播放| 亚洲乱码中文字幕综合234| 国产9色在线 | 日韩|