在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GULP1 Antibody, FITC conjugated

GULP1 Antibody, FITC conjugated

  • 中文名稱：
    GULP1兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA887007LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) GULP1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GULP1
  • 別名：
    CED6 antibody; Cell death protein 6 homolog antibody; Engulfment adapter protein antibody; Engulfment adaptor PTB domain containing 1 antibody; GULP antibody; GULP; engulfment adaptor PTB domain containing 1 antibody; GULP1 antibody; GULP1_HUMAN antibody; Protein GULP antibody; PTB domain adapter protein CED 6 antibody; PTB domain adapter protein CED-6 antibody; PTB domain adaptor protein CED6 antibody; PTB domain-containing engulfment adapter protein 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human PTB domain-containing engulfment adapter protein 1 protein (199-279AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.
  • 基因功能參考文獻：
    1. This study highlights and provides new implications for the role of GULP1 associated molecular mechanism(s) in COPD-emphysema development or progression. PMID: 28284325
    2. GULP1 only mediates LRP1 transactivation PMID: 23167255
    3. The apoptotic engulfment protein Ced-6 participates in clathrin-mediated yolk uptake in Drosophila egg chambers. PMID: 22398720
    4. GULP expression positively regulates TGF-beta signaling leading to growth inhibition, this may represent an attractive target to achieve TGF-beta responsiveness in ovarian cells. PMID: 22451657
    5. This study identify GULP1 as a novel neuronal amyloid-beta precursor protein interacting protein that alters trafficking and processing of amyloid-beta precursor protein. PMID: 20674096
    6. overexpression of GULP1 enhanced the generation of APP CTFs (C-terminal fragments) and Abeta, whereas knockdown of GULP1 suppressed APP CTFs and Abeta production. PMID: 21486224
    7. the GULP1 gene and the apoptotic engulfment pathway are involved in schizophrenia in subjects of European ancestry PMID: 19721717
    8. Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP). PMID: 11729193
    9. GULP is a likely downstream molecule in the stabilin-2-mediated signaling pathway and plays an important role in stabilin-2-mediated phagocytosis PMID: 18230608
    10. Phosphatidylserine-recognizing SR-BI activates associated GULP; activated GULP induces MAPK phosphorylation; activated MAPK increases GTP-bound Rac1; and activated Rac1 induces a rearrangement of the actin cytoskeleton. PMID: 19122200

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Note=May associate with the cytoplasmic side of the plasma membrane and early endosomes.
  • 蛋白家族：
    Ced-6 family
  • 組織特異性：
    Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary.
  • 數據庫鏈接：

    HGNC: 18649

    OMIM: 608165

    KEGG: hsa:51454

    STRING: 9606.ENSP00000352047

    UniGene: Hs.470887



主站蜘蛛池模板： 亚洲妓女综合网99| 久青青视频在线观看久| 久久精品国产丝袜人妻 | 色播亚洲视频在线观看| 国产av区男人的天堂| 日本一卡2卡3卡4卡免费乱码网站| 国产人成无码视频在线观看| 97精品人妻一区二区三区香蕉 | 蜜桃无码一区二区三区| 亚洲人成网亚洲欧洲无码久久| 久久久久欧美精品观看| 疯狂的欧美乱大交| 在线a视频网站| 亚洲2021av天堂手机版| 国产成人av在线影院无毒| 精品欧美一区二区三区久久久| 高清欧美性猛交xxxx黑人猛交| 夜夜春亚洲嫩草影院| 亚洲欧洲中文日韩乱码av| 亚洲婷婷综合色高清在线| 国产99久久久国产精品免费看| 欧美性生交活xxxxxdddd| 欧洲精品一线二线三线区别| 57pao成人国产永久免费视频| 硬了进去湿好大娇喘视频| 久久久国产99久久国产久一| 亚洲一区二区三区小说| 国产av精国产传媒| 欧美精品黑人粗大| 国产精品白浆无码流出视频| 在线播放国产一区二区三区| 久久影院九九被窝爽爽| 成人性无码专区免费视频| 国产成人精品一区二区在线小狼 | 亚洲精品中文字幕乱码三区| 四川老熟女下面又黑又肥| 亚洲国产成人久久一区久久| 久久精品国产精品国产精品污| 国产成人精品男人的天堂| 国产精品jk白丝在线播放| 国产乱子伦精品无码码专区|