在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GUCY1B3 Antibody

  • 中文名稱:
    GUCY1B3兔多克隆抗體
  • 貨號:
    CSB-PA002672
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of HuvEc cells using GCS-β-1 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    GC-S-beta-1 antibody; GC-SB3 antibody; GCbeta1 antibody; GCS beta 1 antibody; GCS beta 3 antibody; GCS-beta-1 antibody; GCS-beta-3 antibody; GCYB1_HUMAN antibody; guanylate cyclase 1; soluble; beta 3 antibody; Guanylate cyclase soluble beta 1 chain antibody; Guanylate cyclase soluble subunit beta-1 antibody; Guanylate cyclase soluble subunit beta-3 antibody; GUC1B3 antibody; GUCSB3 antibody; GUCY1B1 antibody; Gucy1b1; antibody; GUCY1B3 antibody; SGC antibody; Soluble guanylate cyclase small subunit antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the N-terminal region of Human GCS-β-1.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP.
  • 基因功能參考文獻:
    1. Our observations revealed that rs7638A/C polymorphism of GUCY1B3 and the longer telomere length inclined toward adaptation to high altitude. PMID: 29443612
    2. Inhibition of HDAC3 with targeted therapy could benefit treatment of the diseases associated with sGCbeta1 down-regulation and/or deficiency such as cancer and several vascular-related diseases. PMID: 27279362
    3. The kinetics of heme loss from oxidized sGC was monitored by a new method based on the heme group de-quenching the fluorescence of FlAsH-EDT2. PMID: 26876536
    4. Gene expression in dendritic cells of CCL5 and CXCL5 as well as TIMP1 and GUCY1B3 showed a significant increase within the first 4 days after trauma. PMID: 23179318
    5. The results indicate that in comparison with the alpha-1 beta-1 isoform, the brain alpha-2 beta-1 isoform exhibits a distinctly different CO/NO affinity and binding rate in favor of NO signaling. PMID: 22426988
    6. Data show that show that it is possible to directly monitor the sGC haem oxidation state in intact cells. By inserting the TC motif into the coding sequence of the beta1 subunit of sGC in transiently transfected Chinese hamster ovary cells. PMID: 21858179
    7. recombinant soluble guanylate cyclase (sGC) beta1 subunit and truncated N-terminal fragments expressed in E. coli; studied interaction between NO and sGC and schematic mechanism was proposed; study provides insights into structure and NO-binding of sGC PMID: 20063108
    8. Results show that NOGCbeta1 and GC-A interact and that NOGCbeta1 regulates atrial natriuretic peptide signaling in HK-2 cells. PMID: 20024606
    9. The mutant analysis indicated an importance for not only certain dimerization residue positions, but also an important role for other faces of the coiled coil dimer which might perhaps interact with adjacent domains PMID: 20105301
    10. Although soluble guanylate cyclase(sGC) beta1-subunit expression was increased in mononuclear cells from patients with erectile dysfunction, the sGC activity was reduced PMID: 16528291

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Adenylyl cyclase class-4/guanylyl cyclase family
  • 組織特異性:
    Detected in brain cortex and cerebellum (at protein level).
  • 數據庫鏈接:

    HGNC: 4687

    OMIM: 139397

    KEGG: hsa:2983

    STRING: 9606.ENSP00000264424

    UniGene: Hs.77890



主站蜘蛛池模板: 97人洗澡人人澡人人爽人人模| 国产精品自在在线午夜免费| 天堂无码人妻精品av一区| 无码一区二区| 国产乡下三级全黄三级bd| 亚洲性无码av在线| 欧美人禽杂交狂配免费看| 日韩一区二区三区四区区区| 亚洲 欧美 变态 另类 综合| 成年女人a毛片免费视频| 电影内射视频免费观看| 内谢少妇xxxxx8老少交| 成人午夜福利视频| 99re热这里只有精品视频| 亚洲系列一区中文字幕| 性色av一区二区三区人妻| 国产边打电话边被躁视频| 免费人妻av无码专区| 亚洲中文在线播放一区| 色综合a怡红院怡红院| 成人无码精品一区二区三区亚洲区| 国模无码一区二区三区| 浪荡女天天不停挨cao日常视频| 国产成人午夜精品影院| 18禁免费无码无遮挡不卡网站| 高清无码一区二区在线观看吞精| 久久亚洲中文无码咪咪爱| 亚洲欧洲日本综合aⅴ在线 | 疯狂做受xxxx高潮欧美日本| 女人与牲口性恔配视频免费| 天堂中文官网在线| 中文字幕无线码| 日本妇人成熟免费视频| 国产精品99爱免费视频| 亚洲最大天堂无码精品区| 国产乱妇乱子在线播放视频| 亚洲精品无码不卡在线播放he| 国产18禁黄网站免费观看| 欧美丰满熟妇bbbbbb百度| www亚洲精品久久久| 少妇人妻中文字幕污|