在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GTSE1 Antibody

  • 中文名稱:
    GTSE1兔多克隆抗體
  • 貨號:
    CSB-PA010041GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    GTSE1 antibody; G2 and S phase-expressed protein 1 antibody; GTSE-1 antibody; Protein B99 homolog antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Human GTSE1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression.
  • 基因功能參考文獻:
    1. G2 and S-phase expressed 1 (GTSE1) expression promotes AM progression and correlates with clinical outcomes of patients with acral melanoma (AM), and may represent a promising therapeutic target to suppress AM progression. PMID: 29660787
    2. GTSE1 is expressed exclusively in late G2 and M phase. From nuclear envelope breakdown until anaphase onset, GTSE1 binds preferentially to the most stable mitotic spindle microtubules and promotes their turnover. PMID: 28821562
    3. Results indicated for the first time that overexpression of GTSE1 was involved in the progress of HCC, enhancing proliferation and promoting cell invasion in HCC cells. PMID: 27240802
    4. Study identifies GTSE1 as a biomarker for cisplatin resistance in gastric cancer cells and suggests its repressive role in cisplatin induced apoptosis making it a potential therapeutic target for better clinical management of gastric cancer patients. PMID: 26209226
    5. GTSE1 is a microtubule plus-end tracking protein that regulates EB1-dependent cell migration. PMID: 23236459
    6. GTSE1 is overexpressed dramatically in lung cancer patients' tissues. PMID: 22292647
    7. Data show that G2 and S-phase-expressed 1 (GTSE1) protein, a negative regulator of p53, is required for G2 checkpoint recovery and that Plk1 phosphorylation of GTSE1 promotes its nuclear localization. PMID: 20577264
    8. hGTSE-1 mediated-p21(CIP1/WAF1) stabilization is clearly involved in the ability of cells to counteract cytotoxicity induced by the microtubule poison paclitaxel. PMID: 20018861
    9. GTSE-1 controls DNA damage-induced apoptosis by affecting p53 function PMID: 12750368
    10. requires an intact nuclear export signal and functional Mdm2 for the regulation of p53 PMID: 14707141

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Note=Associated with microtubules.
  • 數據庫鏈接:

    HGNC: 13698

    OMIM: 607477

    KEGG: hsa:51512

    STRING: 9606.ENSP00000415430

    UniGene: Hs.386189



主站蜘蛛池模板: 精品人妻系列无码一区二区三区 | 精品无码专区久久久水蜜桃| 成人国产一区二区精品小说| 无码视频一区二区三区在线观看| 国内精品伊人久久久久7777| 99久久国产露脸精品国产麻豆 | 色综合天天综合天天更新| 亚洲中文字幕国产综合| 国产欧美精品区一区二区三区| 国产午夜精品无码| 日韩精品无码免费专区网站| 人妻丰满熟妇av无码区动漫| 好吊色欧美一区二区三区四区| 亚洲人成色4444在线观看| 少妇与子乱在线观看| 亚洲中文无码人a∨在线| 欧美人与动牲猛交a欧美精品 | 曰韩人妻无码一区二区三区综合部| 人妻被按摩师玩弄到潮喷| 100禁毛片免费40分钟视频| 亚洲国产成人精品无码区在线| 亚洲aⅴ天堂av天堂无码麻豆| 中国女人大白屁股ass| 97色偷偷色噜噜男人的天堂| 一区二区三区内射美女毛片| 99视频在线精品免费观看6| 中文日产乱幕九区无线码| 国产成人国产在线观看| 少妇性饥渴无码a区免费| 久久超碰精品一夜七次郎| 色视频综合无码一区二区三区| 中文字幕一区二区三区四区五区 | 中文字幕 乱码 中文乱码视频| 男女后进式猛烈xx00动态图片| 强开小婷嫩苞又嫩又紧视频韩国 | 亚洲成av人片无码bt种子下载| 九九热爱视频精品视频16| 毛片无码国产| 精品视频一区二区三区中文字幕| 最新在线精品国产福利| 日韩精品人成在线播放|