在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GSC Antibody, Biotin conjugated

  • 中文名稱:
    GSC兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA009950LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GSC Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GSC
  • 別名:
    Goosecoid antibody; goosecoid homeobox antibody; GSC antibody; GSC_HUMAN antibody; Homeobox protein goosecoid antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Homeobox protein goosecoid protein (43-127AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring. Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals.
  • 基因功能參考文獻:
    1. Performed mutational analysis of TCOF1, GSC, and HOXA2 to determine the mutational features of the 3 genes in Chinese patients with Treacher Collins syndrome. PMID: 27526242
    2. We find that DIGIT is divergent to Goosecoid (GSC) and expressed during endoderm differentiation. Deletion of the SMAD3-occupied enhancer proximal to DIGIT inhibits DIGIT and GSC expression and definitive endoderm differentiation. PMID: 27705785
    3. 5 genomic variants in GSC, HOXA2 and PRKRA were identified through mutational analysis in Chinese patients with microtia. PMID: 28109504
    4. GSC is also a prognostic factor for poor survival and metastasis of HCC, which suggests its potential as a therapeutic target for metastatic HCC. PMID: 25343336
    5. Results suggest that GSC is the most potential biomarker of drug response and poor prognosis in ovarian serous carcinomas. PMID: 24858567
    6. EtOH exposure increased the expression of an organizer specific gene, goosecoid, in human embryonic carcinoma cells. PMID: 23378141
    7. SAMS, a syndrome of short stature, auditory-canal atresia, mandibular hypoplasia, and skeletal abnormalities is a unique neurocristopathy caused by mutations in Goosecoid. PMID: 24290375
    8. GSC represses EVX1 expression and is required for development of anterior primitive-streak-like cell progeny in response to activin. PMID: 22178155
    9. The goosecoid gene mutation in exon 3 may be involved in the malformation events (microtia) in this family. PMID: 20195123
    10. Goosecoid promotes tumor cell malignancy and suggest that other conserved organizer genes may function similarly in human cancer PMID: 17142318
    11. GSC protein might contribute to the observed phenotype. PMID: 18074379

    顯示更多

    收起更多

  • 相關疾病:
    Short stature, auditory canal atresia, mandibular hypoplasia, skeletal abnormalities (SAMS)
  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Paired homeobox family, Bicoid subfamily
  • 數據庫鏈接:

    HGNC: 4612

    OMIM: 138890

    KEGG: hsa:145258

    STRING: 9606.ENSP00000238558

    UniGene: Hs.440438



主站蜘蛛池模板: 少妇无码一区二区二三区| 无码少妇一区二区性色av| 无码av大香线蕉伊人久久| 国产美女在线精品免费观看网址 | 最美女人体内射精一区二区| 久久精品久久久久观看99水蜜桃| 任我撸在线视频| 丝袜自慰一区二区三区| 成人午夜无码精品免费看| 国产乱子伦一区二区三区=| 国产亚洲精品久久久久四川人| 又粗又大又硬又长又爽| 色综合久久中文娱乐网| 国产欧美综合在线观看第十页| 国产成人不卡无码免费视频| 国产精品麻豆欧美日韩ww| 男人扒开添女人下部免费视频| 女人被狂c到高潮视频网站| 99久久精品国产一区二区| 欧美性受xxxx白人性爽| 亚洲最大天堂无码精品区| 久久久精品2020免费观看| 久久精品国产99精品亚洲| 中文字幕日韩人妻无码| 中文字幕人成乱码在线观看| 中文字幕日本特黄aa毛片| 亚洲一区二区三区无码av| 亚洲日韩一区精品射精| 日本被黑人强伦姧人妻完整版| 国内大量揄拍人妻在线视频| 国产成人亚洲综合图区| 性xxxx欧美老妇胖老太性多毛 | 国产真实的和子乱拍在线观看 | 午夜一区一品日本| 性人久久久久| 超碰国产天天做天天爽| 狠狠躁天天躁无码中文字幕| 亚洲精品国产精华液| 天天拍夜夜添久久精品| 他掀开裙子把舌头伸进去添视频| 国产精品成熟老女人|