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GRK7 Antibody, HRP conjugated

  • 中文名稱:
    GRK7兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA009929LB11HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GRK7 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    GRK7 antibody; GPRK7 antibody; Rhodopsin kinase GRK7 antibody; EC 2.7.11.14 antibody; G protein-coupled receptor kinase 7 antibody; G protein-coupled receptor kinase GRK7 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Rhodopsin kinase protein (342-550AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO).
  • 基因功能參考文獻:
    1. Defects in GRK1 or GRK7 cause patients to suffer from an inability to properly deactivate rhodopsin leading to problems with recovery and dark adaptation. PMID: 22183412
    2. Phosphorylation of GRK1 and GRK7 by PKA occurs in the dark, when cAMP levels in photoreceptor cells are elevated. PMID: 15946941
    3. synthesis of 29 of GRK1 or GRK7 partial peptides that cover the entire sequence of GRK1/GRK7, to see which interacts with recoverin. PMID: 18266817
  • 亞細胞定位:
    Membrane; Lipid-anchor.
  • 蛋白家族:
    Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily
  • 組織特異性:
    Retinal cones, outer and inner segments.
  • 數據庫鏈接:

    HGNC: 17031

    OMIM: 606987

    KEGG: hsa:131890

    STRING: 9606.ENSP00000264952

    UniGene: Hs.680654



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