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  4. GRK7 Antibody，Biotin conjugated

GRK7 Antibody，Biotin conjugated

  • 中文名稱：
    GRK7兔多克隆抗體，Biotin偶聯
  • 貨號：
    CSB-PA009929LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) GRK7 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    GRK7 antibody; GPRK7 antibody; Rhodopsin kinase GRK7 antibody; EC 2.7.11.14 antibody; G protein-coupled receptor kinase 7 antibody; G protein-coupled receptor kinase GRK7 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Rhodopsin kinase protein (342-550AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Antigen Affinity purified & Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO).
  • 基因功能參考文獻：
    1. Defects in GRK1 or GRK7 cause patients to suffer from an inability to properly deactivate rhodopsin leading to problems with recovery and dark adaptation. PMID: 22183412
    2. Phosphorylation of GRK1 and GRK7 by PKA occurs in the dark, when cAMP levels in photoreceptor cells are elevated. PMID: 15946941
    3. synthesis of 29 of GRK1 or GRK7 partial peptides that cover the entire sequence of GRK1/GRK7, to see which interacts with recoverin. PMID: 18266817
  • 亞細胞定位：
    Membrane; Lipid-anchor.
  • 蛋白家族：
    Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily
  • 組織特異性：
    Retinal cones, outer and inner segments.
  • 數據庫鏈接：

    HGNC: 17031

    OMIM: 606987

    KEGG: hsa:131890

    STRING: 9606.ENSP00000264952

    UniGene: Hs.680654



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