在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GRIK4 Antibody, HRP conjugated

  • 中文名稱:
    GRIK4兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA619054LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GRIK4 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    EAA 1 antibody; EAA1 antibody; Excitatory amino acid receptor 1 antibody; GluK4 antibody; Glutamate receptor antibody; Glutamate receptor ionotropic kainate 4 antibody; Glutamate receptor ionotropic kainate 4 precursor antibody; Glutamate receptor KA 1 antibody; Glutamate receptor KA 1precursor antibody; Glutamate receptor KA-1 antibody; Glutamate receptor KA1 antibody; Glutamate receptor; ionotropic kainate 4 antibody; GRIK 4 antibody; GRIK antibody; Grik4 antibody; GRIK4_HUMAN antibody; ionotropic kainate 4 antibody; KA 1 antibody; KA1 antibody; OTTHUMP00000045951 antibody; OTTHUMP00000231881 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Glutamate receptor ionotropic, kainate 4 protein (826-956AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.
  • 基因功能參考文獻:
    1. the GRIK4 polymorphisms genotypes were distributed as follows: rs79526501: CC696: 16, CG302: 274, GG31: 35; rs11218016: CC455: 483, CT473: 436, TT101: 108; and rs6589847: AA32: 29, AG307: 314, GG690: 686. However, there was no significant difference in allelic or genotypic frequency distributions between patients and controls. We did not find any significant association between GRIK4 polymorphisms and schizophrenia. PMID: 28658089
    2. Results firstly indicated that rs56275759 of GRIK4 gene might be associated with major depressive disorder in Chinese Han population. PMID: 28583584
    3. This study showed the lower GluK4 mRNA levels in pregnant women. PMID: 28284346
    4. Data suggest the involvement of glutamate receptor, ionotropic, kainate 4 protein (GRIK4) in treatment-resistant depression (TRD) and in the risk of developing psychotic symptoms during depressive episodes. PMID: 26139080
    5. Subjects possessing the C allele or CC genotype of the GRIK4 polymorphism rs1954787 are more likely to respond to antidepressant treatment. PMID: 25303296
    6. The deletion allele affords protection against bipolar disorder through increased KA1 protein abundance in neuronal cells. PMID: 22052594
    7. Activation of kainate receptors could serve as a novel mechanism for enhancing B cell activation and immunoglobulin production. PMID: 21215464
    8. The GRIK4 single nucleotide polymorphism (rs12800734) shows a strong association with disease remission in antidepressant treatment. PMID: 19924111
    9. Cytogenetic and genetic findings provide molecular evidence for common etiologies for schizophrenia and and bipolar disorder and further support the 'glutamate hypothesis' of psychotic illness. PMID: 16819533
    10. An insertion/deletion (indel) variant in the 3' untranslated region (3'UTR) of the GRIK4 gene in subjects carrying the protective bipolar disorder haplotype was found. PMID: 18824690
    11. This report provides the first evidence that genetic variation in the GRIK4 gene modulates hippocampal function. PMID: 19384319

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Glutamate-gated ion channel (TC 1.A.10.1) family, GRIK4 subfamily
  • 數據庫鏈接:

    HGNC: 4582

    OMIM: 600282

    KEGG: hsa:2900

    STRING: 9606.ENSP00000404063

    UniGene: Hs.538738



主站蜘蛛池模板: 欧美国产日产一区二区| 熟女人妻视频| 99久久精品日本一区二区免费| 青草影院内射中出高潮-百度| 99j久久精品久久久久久| 亚洲欧洲精品a片久久99| 五月天精品视频在线观看| 久久精品国产清自在天天线 | 成人午夜精品无码区| 久久久喷潮一区二区三区| 18禁真人抽搐一进一出免费| 亚洲丰满熟女一区二区v| 久久精品女人天堂av| 中文字幕人妻熟女av| 99久久精品国产一区二区| 亚洲人成伊人成综合网久久久| 内射老妇bbwx0c0ck| 国产人妻久久精品二区三区特黄 | 日韩理论午夜无码| 69风韵老熟女口爆吞精| 亚洲人成色77777| 日韩一本之道一区中文字幕| 四虎影视无码永久免费| 色婷婷五月综合色啪网| 极品粉嫩嫩模大尺度无码视频| 久久视频在线视频| 欧美亚洲色aⅴ大片| 久久精品水蜜桃av综合天堂| 久久久久无码精品国产不卡| 国产sm调教折磨视频失禁| 欧美 亚洲 日韩 中文2019 | 久久精品国产一区二区电影| 久久人搡人人玩人妻精品首页 | 精品国产乱码久久久软件下载| 国内揄拍国内精品少妇| 性人久久久久| 玩弄了裸睡少妇人妻野战| 无码毛片一区二区本码视频| 亚洲欧美日韩在线不卡| 国产精品igao视频网| 乌克兰性欧美精品高清|