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GRHPR Antibody, FITC conjugated

  • 中文名稱:
    GRHPR兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA009897HC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GRHPR Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GRHPR
  • 別名:
    GLXR antibody; glycerate 2 dehydrogenase antibody; GLYD antibody; Glyoxylate reductase/hydroxypyruvate reductase antibody; Grhpr antibody; GRHPR_HUMAN antibody; OTTHUMP00000021379 antibody; OTTHUMP00000021380 antibody; OTTHUMP00000046131 antibody; PH 2 antibody; PH2 antibody; Primary hyperoxaluria type 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Glyoxylate reductase/hydroxypyruvate reductase protein (1-328AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate.
  • 基因功能參考文獻:
    1. GRHPR was genotyped in Japanese patients with PH2 and all GRHPR mutations described to date were reviewed in terms of geographic and ethnic association PMID: 24116921
    2. Our findings suggest that the GRHPR defect in noncancerous tissues may represent an independent predictor of poor survival for hepatocellular carcinoma patients after curative resection PMID: 23486161
    3. GRHPR directly interacts with SVCT1. PMID: 23599041
    4. substrate specificity of human glyoxylate reductase PMID: 16756993
    5. the GRHPR gene may have a role in primary hyperoxaluria type 2 in a Japanese patient [case report] PMID: 17510093

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  • 相關疾病:
    Hyperoxaluria primary 2 (HP2)
  • 蛋白家族:
    D-isomer specific 2-hydroxyacid dehydrogenase family
  • 組織特異性:
    Ubiquitous. Most abundantly expressed in the liver.
  • 數據庫鏈接:

    HGNC: 4570

    OMIM: 260000

    KEGG: hsa:9380

    STRING: 9606.ENSP00000313432

    UniGene: Hs.155742



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