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  4. GPX8 Antibody

GPX8 Antibody

  • 中文名稱：
    GPX8兔多克隆抗體
  • 貨號：
    CSB-PA848417LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunofluorescent analysis of Hela cells using CSB-PA848417LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA848417LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA848417LA01HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) GPX8 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    GPX8; UNQ847/PRO1785; Probable glutathione peroxidase 8; GPx-8; GSHPx-8
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Probable glutathione peroxidase 8 protein (41-209AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，GPX8 Antibody (CSB-PA848417LA01HU)，的標記方式是Non-conjugated。對于GPX8 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA848417LB01HU GPX8 Antibody, HRP conjugated ELISA
    FITC CSB-PA848417LC01HU GPX8 Antibody, FITC conjugated
    Biotin CSB-PA848417LD01HU GPX8 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 基因功能參考文獻：
    1. Study provides evidence that the conserved N-terminal transmembrane domain of GPX8, in addition to its enzymatic activity, is essential for regulating Ca(2+) dynamics revealing a novel level of integration between redox-related proteins and Ca(2+) signaling/homeostasis. PMID: 28129698
    2. GPX8 is transcriptionally regulated by HIFalpha and modulates growth factor signaling in HeLa cells. PMID: 25557012
    3. Along with the induction of GPX8 in ER-stressed cells, these findings question a ubiquitous role of Ero1alpha as a producer of cytoplasmic ROS under ER stress PMID: 24566470
    4. Quantitative proteomics identifies the membrane-associated peroxidase GPx8 as a cellular substrate of the hepatitis C virus NS3-4A protease. PMID: 23929719
    5. GPx8 labeled as secreted glutathione peroxidase, is actually endoplasmic reticulum-resident protein disulfide isomerase peroxidase PMID: 21215271

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  • 亞細胞定位：
    Membrane; Single-pass membrane protein.
  • 蛋白家族：
    Glutathione peroxidase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 33100

    KEGG: hsa:493869

    STRING: 9606.ENSP00000423822

    UniGene: Hs.289044



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