在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GPR31 Antibody

GPR31 Antibody

  • 中文名稱：
    GPR31兔多克隆抗體
  • 貨號：
    CSB-PA008927
  • 規(guī)格：
    ￥1090
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    GPR31; 12-(S-hydroxy-5,8,10,14-eicosatetraenoic acid receptor; 12-(S-HETE receptor; 12-HETER; G-protein coupled receptor 31; GPR31/12-HETER
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human GPR31.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    High-affinity receptor for 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12-S-HETE), with much lower affinities for other HETE isomers. 12-S-HETE is a eicosanoid, a 12-lipoxygenase (ALOX12) metabolite of arachidonic acid, involved in many physiologic and pathologic processes. 12-S-HETE-binding leads to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B pathways leading to cell growth. Plays a crucial role for proliferation, survival and macropinocytosis of KRAS-dependent cancer cells by mediating the translocation of KRAS from the endoplasmic reticulum to the plasma membrane (PM) and its association with the PM. Contributes to enhanced immune responses by inducing dendrite protrusion of small intestinal CX3CR1(+) phagocytes for the uptake of luminal antigens. Acts also as a key receptor for 12-(S)-HETE-mediated liver ischemia reperfusion injury.; Proton-sensing G protein-coupled receptor.
  • 基因功能參考文獻：
    1. Suggest that GPR31 acts as a secretory pathway chaperone for KRAS4B in tumor cells. PMID: 28619714
    2. The data implicate 12-HETER1 in a critical new role in the regulation of prostate cancer progression and offer a novel alternative target for therapeutic intervention. PMID: 26965684
    3. 12-HETER represents the first identified high affinity receptor for the 12-(S)-HETE hydroxyl fatty acids. PMID: 21712392
  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 數(shù)據庫鏈接：

    HGNC: 4486

    OMIM: 602043

    KEGG: hsa:2853

    STRING: 9606.ENSP00000355799

    UniGene: Hs.248124



主站蜘蛛池模板： 亚色九九九全国免费视频| 8av国产精品爽爽ⅴa在线观看 | 国内精品人妻久久毛片app| 色播亚洲视频在线观看| 蜜乳av久久久久久久久久久| 国产亚洲精品a久久777777| 精品无码国产av一区二区三区| 小sao货水好多真紧h无码视频| 亚洲综合色婷婷六月丁香宅男大增| 狠狠精品久久久无码中文字幕| 韩国三级l中文字幕无码| 国产精品无码一区二区三区在 | 无码av天天av天天爽| 国产精品色拉拉| 国内精品久久人妻互换| 国产精品久线在线观看| 亚洲国产成人久久综合碰| 欧美做受视频播放| 少妇人妻在线视频| 精品久久久久成人码免费动漫| 老色鬼永久视频网站| 无码人妻久久一区二区三区app | 久久综合精品无码av一区二区三区| 国产明星裸体xxxx视频| 亚洲第一无码xxxxxx| 久久欧美国产伦子伦精品 | 欧美激情综合色综合啪啪五月| 午夜福制92视频| 少妇被又大又粗又爽毛片久久黑人| 艳妇臀荡乳欲伦交换h在线观看 | 国产精品人成视频免费国产| 蜜臀av无码精品人妻色欲| 成人免费看黄网站yyy456| 欧美综合自拍亚洲综合区| 麻豆国产av超爽剧情系列| 男女高潮又爽又黄又无遮挡| 欧美videos另类极品| 超清无码波多野吉衣中文| 中文字幕久久熟女蜜桃| 无遮挡午夜男女xx00动态| 亚洲另类色区欧美日韩图片|