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GPR133 Antibody

  • 中文名稱:
    GPR133兔多克隆抗體
  • 貨號:
    CSB-PA008902
  • 規格:
    ¥1090
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    DKFZp434B1272 antibody; FLJ16770 antibody; G protein coupled receptor 133 antibody; G protein coupled receptor PGR25 antibody; G-protein coupled receptor PGR25 antibody; GP133_HUMAN antibody; Gpr133 antibody; MGC138512 antibody; MGC138514 antibody; PGR25 antibody; Probable G-protein coupled receptor 133 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Monkey
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human GPR133.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IF, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

平均分:
5.0分 - 1 個評價

實驗應用:WB

樣品信息:細胞裂解液

稀釋比:1:1000

產品評價: 我使用CSB-PA008902抗體進行細胞中GPR133蛋白表達的WB檢測,因為是膜蛋白所以用的37℃,30min變性蛋白。上樣量為15ug總蛋白,條帶很清晰,結果還算不錯。

By 劉老師

靶點詳情

  • 功能:
    Orphan receptor. Signals via G(s)-alpha family of G-proteins. Has protumorigenic function especially in glioblastoma.
  • 基因功能參考文獻:
    1. The results show that a broad spectrum of functionally relevant ADGRD1 variants is present in the human population which may cause clinically relevant phenotypes, while being compatible with life when heterozygous. PMID: 27516204
    2. Cell adhesion receptor GPR133 couples to Gs protein PMID: 22025619
    3. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    4. A role for GPR133 protein in affecting the length of the electrocardiographic RR interval and heart rate. PMID: 20031603
    5. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 20031603
    6. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 19729412

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  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
  • 組織特異性:
    Up-regulated in CD133(+) cell population of glioblastoma.
  • 數據庫鏈接:

    HGNC: 19893

    OMIM: 613639

    KEGG: hsa:283383

    STRING: 9606.ENSP00000261654

    UniGene: Hs.719239



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