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  4. GPR133 Antibody

GPR133 Antibody

  • 中文名稱：
    GPR133兔多克隆抗體
  • 貨號：
    CSB-PA008902
  • 規格：
    ￥1090
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    DKFZp434B1272 antibody; FLJ16770 antibody; G protein coupled receptor 133 antibody; G protein coupled receptor PGR25 antibody; G-protein coupled receptor PGR25 antibody; GP133_HUMAN antibody; Gpr133 antibody; MGC138512 antibody; MGC138514 antibody; PGR25 antibody; Probable G-protein coupled receptor 133 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Monkey
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human GPR133.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

平均分:
5.0分 - 1 個評價

實驗應用：WB

樣品信息：細胞裂解液

稀釋比：1:1000

產品評價： 我使用CSB-PA008902抗體進行細胞中GPR133蛋白表達的WB檢測，因為是膜蛋白所以用的37℃，30min變性蛋白。上樣量為15ug總蛋白，條帶很清晰，結果還算不錯。

By 劉老師

靶點詳情

  • 功能：
    Orphan receptor. Signals via G(s)-alpha family of G-proteins. Has protumorigenic function especially in glioblastoma.
  • 基因功能參考文獻：
    1. The results show that a broad spectrum of functionally relevant ADGRD1 variants is present in the human population which may cause clinically relevant phenotypes, while being compatible with life when heterozygous. PMID: 27516204
    2. Cell adhesion receptor GPR133 couples to Gs protein PMID: 22025619
    3. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    4. A role for GPR133 protein in affecting the length of the electrocardiographic RR interval and heart rate. PMID: 20031603
    5. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 20031603
    6. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 19729412

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  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
  • 組織特異性：
    Up-regulated in CD133(+) cell population of glioblastoma.
  • 數據庫鏈接：

    HGNC: 19893

    OMIM: 613639

    KEGG: hsa:283383

    STRING: 9606.ENSP00000261654

    UniGene: Hs.719239



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