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GPR110 Antibody

  • 中文名稱:
    GPR110兔多克隆抗體
  • 貨號:
    CSB-PA002753
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of 3T3 cells using GPR110 Polyclonal Antibody
    • Western Blot analysis of NIH-3T3 K562 cells using GPR110 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    G protein coupled receptor 110 antibody; G protein coupled receptor KPG_012 antibody; G protein coupled receptor PGR19 antibody; G-protein coupled receptor KPG_012 antibody; G-protein coupled receptor PGR19 antibody; GP110_HUMAN antibody; GPR110 antibody; HGPCR36 antibody; KPG_012 antibody; PGR19 antibody; Probable G protein coupled receptor 110 antibody; Probable G-protein coupled receptor 110 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from the C-terminal region of Human GPR110.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IF, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:40000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Orphan receptor.
  • 基因功能參考文獻:
    1. Study demonstrated orphan G-protein coupled receptor 110 (GPR110, ADGRF1) as the synaptamide receptor, mediating synaptamide-induced bioactivity in a cAMP-dependent manner. PMID: 27759003
    2. High GPR110 expression is associated with CRLF2-rearranged acute lymphoblastic leukemia. PMID: 28866095
    3. ADGRF1 single-nucleotide polymorphisms role in susceptibility to non-small cell lung cancer PMID: 28968839
    4. The results suggested the possible participation of STAT3 instead of ERK in the GPR110 signaling pathways and progression of glioma. PMID: 28728843
    5. GPR56 and GPR110 are activated by exposure of a cryptic tethered agonist PMID: 25918380
    6. GPR110 is an oncogene overexpressed in lung and prostate cancer PMID: 20149256

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  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.; [Isoform 2]: Secreted.
  • 蛋白家族:
    G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
  • 組織特異性:
    Mainly expressed in the kidney. Up-regulated in lung adenocarcinomas and prostate cancers.
  • 數據庫鏈接:

    HGNC: 18990

    OMIM: 617430

    KEGG: hsa:266977

    STRING: 9606.ENSP00000360299

    UniGene: Hs.733762



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