在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GOSR2 Antibody

  • 中文名稱:
    GOSR2兔多克隆抗體
  • 貨號:
    CSB-PA009678LA01HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: GOSR2 antibody at 4µg/ml + Jurkat whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 25, 23 kDa
      Observed band size: 25 kDa
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA009678LA01HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) GOSR2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GOSR2
  • 別名:
    2310032N09Rik antibody; 27 kDa Golgi SNARE protein antibody; Bos1 antibody; EPM6 antibody; Golgi SNAP receptor complex member 2 antibody; Golgi SNARE antibody; Gosr2 antibody; GOSR2_HUMAN antibody; Gs27 antibody; Membrin antibody; SNARE antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Golgi SNAP receptor complex member 2 protein (1-190AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated

    本頁面中的產(chǎn)品,GOSR2 Antibody (CSB-PA009678LA01HU),的標(biāo)記方式是Non-conjugated。對于GOSR2 Antibody,我們還提供其他標(biāo)記。見下表:

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA009678LB01HU GOSR2 Antibody, HRP conjugated ELISA
    FITC CSB-PA009678LC01HU GOSR2 Antibody, FITC conjugated
    Biotin CSB-PA009678LD01HU GOSR2 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
  • 基因功能參考文獻(xiàn):
    1. Recessive mutations in TRAPPC11 and GOSR2 are associated with congenital muscular dystrophy and hypoglycosylation of alpha-dystroglycan. PMID: 29855340
    2. Molecular dynamics (MD) simulations showed that the hydrophobic core, which triggers SNARE complex formation, is compromised due to the glycine-to-tryptophan substitution in both GOSR2 and Bos1. PMID: 28982678
    3. Mutations in GOSR2 reveal stringent secretory pathway demands of dendritic growth and synaptic integrity. PMID: 28978487
    4. review of the phenotype/genotype of GOSR2-associated progressive myoclonus epilepsy [review] PMID: 27618868
    5. The SNAREs(Soluble N-ethylmaleimide-sensitive factor attachment protein receptors), that regulate both the biogenesis and secretion of multiple lysosome-related organelles(LROs). PMID: 26760525
    6. Based on the presented phenotype, we would advise movement disorder specialists to consider mutation analysis of GOSR2 in patients with Ramsay Hunt syndrome, especially when they also have areflexia. PMID: 24458321
    7. A haplotype of the GOSR2 gene is associated with myocardial infarction in Japanese men PMID: 23675987
    8. Single nucleotide polymorphisms in the GOSR2 gene are associated with essential hypertension in Japanese men. PMID: 23313660
    9. GOSR2 gene mutation is associated with progressive myoclonus epilepsy cases, all of whom came from countries bounding the North Sea, extending to the coastal region of Northern Norway. PMID: 23449775
    10. This p.Gly144Trp mutation is equivalent to a loss of function and results in failure of GOSR2 protein to localize to the cis-Golgi. PMID: 21549339
    11. A homozygous mutation in GOSR2 (c.430G>T, p.Gly144Trp), was identified in five apparently unrelated families with a clinically distinct progressive myoclonic epilepsy syndrome. PMID: 21549339
    12. These studies suggest that membrin recruits Arf-1 to the early Golgi and reveal distinct kinetic cycles for Arf-1 at early and late Golgi determined by different sets of Arf regulators and effectors. PMID: 15781476
    13. We found evidence that a SNP in GOSR2 is modestly associated with hypertension in whites from the ARIC study and the WGHS. PMID: 19057520

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Epilepsy, progressive myoclonic 6 (EPM6)
  • 亞細(xì)胞定位:
    Golgi apparatus, cis-Golgi network membrane; Single-pass type IV membrane protein. Golgi apparatus membrane. Endoplasmic reticulum membrane.
  • 蛋白家族:
    GOSR2 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 4431

    OMIM: 604027

    KEGG: hsa:9570

    STRING: 9606.ENSP00000225567

    UniGene: Hs.463278



主站蜘蛛池模板: 婷婷久久久亚洲欧洲日产国码av| 亚洲欧美日韩成人一区| 亚洲精品久久久久久久蜜臀老牛| 丝袜老师高潮呻吟高潮| 精品国产一区二区av麻豆| 男人的天堂在线视频| 国产精品亚洲专区无码web| 国产午夜片无码区在线观看爱情网| 国产精品亚洲а∨无码播放不卡| 国产后入又长又硬| 人人妻人人澡人人爽欧美一区| 麻豆国产人妻欲求不满| 丰满熟女高潮毛茸茸欧洲视频| 精品国产乱码久久久久久婷婷| 狠狠躁日日躁夜夜躁2022麻豆| 青草av久久一区二区三区| 鲁鲁网亚洲站内射污| 久久精品国产99精品国产2021| 无码精品人妻一区二区三区人妻斩| 国产xxxx色视频在线观看| 国产精品女丝袜白丝袜| 日韩人妻一区二区三区免费 | 国自产拍偷拍精品啪啪av| av永久天堂一区二区三区| 国产成人无码av| 欧美日韩亚洲tv不卡久久| av在线 亚洲 天堂| 久久成人麻豆午夜电影| 亚洲欧洲日产国码韩国| 老男人久久青草av高清| 亚洲精品无码国产片| 日韩精品无码视频一区二区蜜桃| 成人一在线视频日韩国产| 白嫩少妇激情无码| 狠狠色综合7777久夜色撩人 | 大地资源中文在线观看官网第二页 | 精品黑人一区二区三区久久| 日韩精品人妻系列一区二区三区| 亚洲综合激情五月丁香六月| 国模小黎自慰gogo人体| 丁香婷婷激情综合俺也去|