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GNB2 Antibody

  • 中文名稱:
    GNB2兔多克隆抗體
  • 貨號(hào):
    CSB-PA009604ESR1HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: GNB2 antibody at 2.22µg/ml
      Lane 1: Mouse lung tissue
      Lane 2: NIH/3T3 whole cell lysate
      Lane 3: Jurkat whole cell lysate
      Lane 4: 293T whole cell lysate
      Lane 5: Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 38, 26 kDa
      Observed band size: 38 kDa
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA009604ESR1HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) GNB2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    G protein beta 2 subunit antibody; G protein subunit beta 2 antibody; G protein subunit beta-2 antibody; GBB2_HUMAN antibody; Gnb2 antibody; Gnb2l1 antibody; Guanine nucleotide binding protein beta 2 subunit antibody; Guanine nucleotide binding protein G I G S G T beta 2 subunit 2 antibody; Guanine nucleotide binding protein G protein beta polypeptide 2 antibody; Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 antibody; OTTHUMP00000174601 antibody; OTTHUMP00000174602 antibody; RACK1 antibody; Receptor for activated C kinase antibody; Receptor of activated protein kinase C 1 antibody; Signal transducing guanine nucleotide binding regulatory protein beta antibody; Transducin beta chain 2 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 protein (1-340AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
  • 基因功能參考文獻(xiàn):
    1. A GNB2 gene mutation is associated with familial sinus node and atrioventricular conduction dysfunction. PMID: 28219978
    2. MIF and GNbeta2 interacted with influenza A H1N1 virus PB1-F2 protein. PMID: 23043599
    3. Results indicate that G protein beta2 (Gbeta2) is required for starvation-induced NF-kappaB activation and constitutive NF-kappaB activity. PMID: 22917497
    4. We conclude that the Gbetagamma complex interacts with the GR and suppresses its transcriptional activity by associating with the transcriptional complex formed on GR-responsive promoters. PMID: 15955845
    5. Recombinant Gbetagamma subunits were used to establish that the Gbeta(2)gamma(2) dimer can selectively reconstitute the inhibition of alpha(1H) channels in isolated membrane patches. PMID: 16973746

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  • 亞細(xì)胞定位:
    Cytoplasm, perinuclear region.
  • 蛋白家族:
    WD repeat G protein beta family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 4398

    OMIM: 139390

    KEGG: hsa:2783

    STRING: 9606.ENSP00000305260

    UniGene: Hs.185172



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