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  4. GNAZ Antibody, FITC conjugated

GNAZ Antibody, FITC conjugated

  • 中文名稱：
    GNAZ兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA009601LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) GNAZ Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GNAZ
  • 別名：
    G(x) alpha chain antibody; GNAZ antibody; GNAZ_HUMAN antibody; Guanine nucleotide-binding protein G(z) subunit alpha antibody; Gz-alpha antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Guanine nucleotide-binding protein G(z) subunit alpha protein (3-140AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
  • 基因功能參考文獻：
    1. GNAZ mutations are associated with melanoma. PMID: 20424519
    2. cGMP-phosphodiesterase 6 can be activated by another cancer-retina antigen, transducin, through Wnt5a-Frizzled-2 cascade, which leads to a lowering of cGMP and an increase in intracellular calcium mobilization. PMID: 19946729
    3. findings suggest that Galphaz signals may attenuate Rho-induced stimulation of SRF-mediated transcription PMID: 15326221
  • 亞細胞定位：
    Membrane; Lipid-anchor.
  • 蛋白家族：
    G-alpha family, G(i/o/t/z) subfamily
  • 數據庫鏈接：

    HGNC: 4395

    OMIM: 139160

    KEGG: hsa:2781

    STRING: 9606.ENSP00000248996

    UniGene: Hs.584760



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