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GMIP Antibody, Biotin conjugated

  • 中文名稱:
    GMIP兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA878952LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GMIP Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GMIP
  • 別名:
    ARHGAP46 antibody; GEM interacting protein antibody; GEM-interacting protein antibody; GMIP antibody; GMIP_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human GEM-interacting protein (719-858AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Stimulates, in vitro and in vivo, the GTPase activity of RhoA.
  • 基因功能參考文獻:
    1. These findings demonstrate a new role of Gem/Gmip/RhoA signaling in cortical actin regulation during early mitotic stages PMID: 25173885
    2. during exocytosis, actin depolymerization commences near the secretory organelle, not the plasma membrane, and secretory granules use a JFC1- and GMIP-dependent molecular mechanism to traverse cortical actin. PMID: 22438581
    3. signalling pathways controlled by two proteins of the Ras superfamily, RhoA and Gem, are linked via the action of the RhoGAP protein Gmip PMID: 12093360
    4. Variations in the GMIP gene can confer susceptibility to major depressive disorder. PMID: 16086184
  • 數據庫鏈接:

    HGNC: 24852

    OMIM: 609694

    KEGG: hsa:51291

    STRING: 9606.ENSP00000203556

    UniGene: Hs.49427



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