GMFB Antibody

說明書

產品詳情

Uniprot No.：

P60983
基因名：

GMFB
別名：

Glia maturation factor beta antibody; GMF antibody; GMF-beta antibody; GMFB antibody; GMFB_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human GMFB
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells.
基因功能參考文獻：
1. GMF-beta is an important player in glioma progression via promoting neovascularization. PMID: 26515590
2. The distribution of GMF-immunoreactive cells in and around amyloid plaques and neurofibrillary tangles suggests involvement of GMF in inflammatory responses through reactive glia and a role of GMF in Alzheimer disease pathology. PMID: 22035352
3. GMF co-localizes with amyloid plaques and neurofibrillary tangles in Alzheimer brains, implicating significant upregulation of GMF expression under conditions of neurodegeneration. PMID: 21835226
4. There is a significant increase in GMF beta protein expression levels in IFN beta-1a treated LX-2 cells. PMID: 18171522
5. GMFB promoted T-cell differentiation into CD4-/CD8+ cells when analysed by two-colour flow cytometry. PMID: 16115230
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蛋白家族：

Actin-binding proteins ADF family, GMF subfamily
數據庫鏈接：

HGNC: 4373

OMIM: 601713

KEGG: hsa:2764

STRING: 9606.ENSP00000350757

UniGene: Hs.151413

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