在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GLMN Antibody

  • 中文名稱:
    GLMN兔多克隆抗體
  • 貨號:
    CSB-PA170354
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA170354(GLMN Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA170354(GLMN Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    GLMN
  • 別名:
    FAP antibody; FAP48 antibody; FAP68 antibody; FK506 binding protein associated protein antibody; FK506-binding protein-associated protein antibody; FKBP associated protein antibody; FKBP-associated protein antibody; FKBP-associated protein, 48-KD antibody; FKBP-associated protein, 68-KD antibody; FKBPAP antibody; GLML antibody; Glmn antibody; GLMN_HUMAN antibody; Glomulin antibody; glomulin, FKBP associated protein antibody; GVM antibody; VMGLOM antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthetic peptide of Human GLMN
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Regulatory component of cullin-RING-based SCF (SKP1-Cullin-F-box protein) E3 ubiquitin-protein ligase complexes. Inhibits E3 ubiquitin ligase activity by binding to RBX1 (via RING domain) and inhibiting its interaction with the E2 ubiquitin-conjugating enzyme CDC34. Inhibits RBX1-mediated neddylation of CUL1. Required for normal stability and normal cellular levels of key components of SCF ubiquitin ligase complexes, including FBXW7, RBX1, CUL1, CUL2, CUL3, CUL4A, and thereby contributes to the regulation of CCNE1 and MYC levels. Essential for normal development of the vasculature. Contributes to the regulation of RPS6KB1 phosphorylation.
  • 基因功能參考文獻:
    1. Our report contributes to document the possible association between the c.395-1G>C mutation of GLMN gene and glomuvenous malformations. PMID: 24961656
    2. FAP48 adipocyte expression plays a key role in HIV-associated lipodystrophy. PMID: 22678819
    3. These data identify glomulin as a permissivity factor for VACV infection and as a potential therapeutic target for inhibition of vaccinia virus (VACV) infection. PMID: 22280104
    4. The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin-1 RING ligase-mediated turnover of Fbw7. PMID: 22405651
    5. A novel GLMN mutation is described in an Italian family with glomuvenous malformations in which some members present with the less commonly observed phenotype of solitary lesions. PMID: 22092580
    6. Describes the characterizations of 14 different mutations in the glomulin gene in patients with glomuvenous malformations. PMID: 11845407
    7. FAP48-FKBP complexes increase IL2 production PMID: 12604780

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Glomuvenous malformations (GVMs)
  • 組織特異性:
    Ubiquitous.
  • 數據庫鏈接:

    HGNC: 14373

    OMIM: 138000

    KEGG: hsa:11146

    STRING: 9606.ENSP00000359385

    UniGene: Hs.49105



主站蜘蛛池模板: 亚洲无线码在线一区观看| 久久亚洲精品国产精品777777| 国产乱子伦视频在线播放| 久久亚洲精品情侣| 免费人成激情视频在线观看 | 欧美伊人色综合久久天天| 五十路熟女一区二区三区| 99国产精品99久久久久久| 久热国产vs视频在线观看| 亚洲va天堂va欧美片a在线| 天堂网www天堂资源网| 亚洲6080yy久久无码产自国产| 日本乱偷人妻中文字幕在线| 欧美mv日韩mv国产网站app| 成人午夜无码专区性视频性视频| 日韩av无码中文无码电影| 国产九九九九九九九a片| 人妻中文字幕无码专区| 国产偷抇久久精品a片69| 亚洲旡码a∨一区二区三区| 中文字幕 乱码 中文乱码视频| 潮喷失禁大喷水aⅴ无码| 亚洲人成电影网站色www两男一女| 国产肉丝袜视频在线观看| 日韩一区二区三区射精-百度| 日日摸日日碰夜夜爽亚洲综合| 国产大片黄在线观看私人影院| 免费无码毛片一区二三区| 99j久久精品久久久久久| 天天躁日日躁aaaxxⅹ| 国产美女精品视频线免费播放| 99国产精品久久久久久久日本竹 | 色窝窝无码一区二区三区成人网站| 国产男女无遮挡猛进猛出 | 亚洲精品成人片在线播放| 亚洲美女精品免费视频| 亚洲精品无码少妇30p| 无码无套少妇毛多18pxxxx| 国产v亚洲v天堂无码久久久| 亚 洲 成 人 网站在线观看| 久久精品一区二区av999|