在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GLMN Antibody

GLMN Antibody

  • 中文名稱：
    GLMN兔多克隆抗體
  • 貨號：
    CSB-PA170354
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA170354(GLMN Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA170354(GLMN Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    GLMN
  • 別名：
    FAP antibody; FAP48 antibody; FAP68 antibody; FK506 binding protein associated protein antibody; FK506-binding protein-associated protein antibody; FKBP associated protein antibody; FKBP-associated protein antibody; FKBP-associated protein, 48-KD antibody; FKBP-associated protein, 68-KD antibody; FKBPAP antibody; GLML antibody; Glmn antibody; GLMN_HUMAN antibody; Glomulin antibody; glomulin, FKBP associated protein antibody; GVM antibody; VMGLOM antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human GLMN
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Regulatory component of cullin-RING-based SCF (SKP1-Cullin-F-box protein) E3 ubiquitin-protein ligase complexes. Inhibits E3 ubiquitin ligase activity by binding to RBX1 (via RING domain) and inhibiting its interaction with the E2 ubiquitin-conjugating enzyme CDC34. Inhibits RBX1-mediated neddylation of CUL1. Required for normal stability and normal cellular levels of key components of SCF ubiquitin ligase complexes, including FBXW7, RBX1, CUL1, CUL2, CUL3, CUL4A, and thereby contributes to the regulation of CCNE1 and MYC levels. Essential for normal development of the vasculature. Contributes to the regulation of RPS6KB1 phosphorylation.
  • 基因功能參考文獻：
    1. Our report contributes to document the possible association between the c.395-1G>C mutation of GLMN gene and glomuvenous malformations. PMID: 24961656
    2. FAP48 adipocyte expression plays a key role in HIV-associated lipodystrophy. PMID: 22678819
    3. These data identify glomulin as a permissivity factor for VACV infection and as a potential therapeutic target for inhibition of vaccinia virus (VACV) infection. PMID: 22280104
    4. The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin-1 RING ligase-mediated turnover of Fbw7. PMID: 22405651
    5. A novel GLMN mutation is described in an Italian family with glomuvenous malformations in which some members present with the less commonly observed phenotype of solitary lesions. PMID: 22092580
    6. Describes the characterizations of 14 different mutations in the glomulin gene in patients with glomuvenous malformations. PMID: 11845407
    7. FAP48-FKBP complexes increase IL2 production PMID: 12604780

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Glomuvenous malformations (GVMs)
  • 組織特異性：
    Ubiquitous.
  • 數據庫鏈接：

    HGNC: 14373

    OMIM: 138000

    KEGG: hsa:11146

    STRING: 9606.ENSP00000359385

    UniGene: Hs.49105



主站蜘蛛池模板： 久久青青草免费线频观| 中文字幕精品久久久久人妻红杏ⅰ| 亚洲色无码专区在线观看精品| 老色鬼永久视频网站| 成 人 a v免费视频在线观看| 精品亚洲aⅴ在线无码播放| 美女内射毛片在线看3d| 欧美性videos高清精品| 丝袜无码一区二区三区| 男女无遮挡猛进猛出免费观看视频| 精品无码乱码av| 免费人成在线观看| 国产乱子伦视频一区二区三区| 国产亚洲精品久久久久久打不开| 国产萌白酱喷水视频在线播放 | 少妇高潮喷水久久久久久久久久| 熟女体下毛毛黑森林| 久久久国产精华液| 男人的天堂免费一区二区视频| а天堂中文最新版在线| 性色av无码一区二区三区人妻| 日韩精品乱码av一区二区 | 水蜜桃亚洲一二三四在线| 国产精品久久久久久久久动漫| 女人爽到喷水的视频大全| 老汉老妇姓交视频| av在线无码专区一区| 强行糟蹋人妻hd中文字幕| 精品www日韩熟女人妻| 天天澡日日澡狠狠欧美老妇| 精品无码国产自产在线观看水浒传| 人妻熟女一区| 国产成人精品高清在线观看99| 国产欧美在线一区二区三| 97国产色伦在色在线播放| 欧美另类videosbestsex日本 | 国产真实自在自线免费精品| 久久精品国自产拍| 免费无遮挡无码永久视频| 久久久久国产一区二区| 亚洲日本中文字幕乱码在线|