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  4. GLIPR2 Antibody, Biotin conjugated

GLIPR2 Antibody, Biotin conjugated

  • 中文名稱：
    GLIPR2兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA880974LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) GLIPR2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GLIPR2
  • 別名：
    5730414A08Rik antibody; C77180 antibody; C9orf19 antibody; GAPR 1 antibody; GAPR-1 antibody; GAPR1_HUMAN antibody; GLI pathogenesis related 2 antibody; Glioma pathogenesis related protein 2 antibody; Glioma pathogenesis-related protein 2 antibody; GliPR 2 antibody; GLIPR2 antibody; Golgi associated plant pathogenesis related protein 1 antibody; Golgi associated PR 1 protein antibody; Golgi-associated plant pathogenesis-related protein 1 antibody; Golgi-associated PR-1 protein antibody; OTTMUSP00000007558 antibody; RP11-421H8.5 antibody; RP23-209M8.2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Golgi-associated plant pathogenesis-related protein 1 protein (2-85AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 基因功能參考文獻：
    1. Here, sequence analyses, structural modeling, mutagenesis combined with pull-down assays, X-ray crystal structure determination and small-angle X-ray scattering were used to investigate the Beclin 1-GAPR-1 interaction. changes in the structure of the equatorial groove combined with the improved dimerization of pentad mutant GAPR-1 are likely to abrogate binding to Beclin 1. PMID: 28876241
    2. This study identified a previously unrecognized role for GAPR-1 to control a unifying TLR4 signaling complex and to regulate type I Interferon signaling activation. PMID: 26678074
    3. Hypoxia promotes epithelial-mesenchymal transition of hepatocellular carcinoma cells via inducing GLIPR-2 expression. PMID: 24204846
    4. GLIPR-2 overexpression in HK-2 cells can potentiate EMT-like processes in this cell type through the ERK1/2 signaling pathway PMID: 23516513
    5. the charge properties of the lipid bilayer can regulate GAPR-1 dynamics as a potential mechanism to modulate GAPR-1 function PMID: 22560898

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  • 亞細(xì)胞定位：
    Golgi apparatus membrane; Lipid-anchor. Note=Binds lipid-enriched microdomains of Golgi membranes not only by ionic interactions but also through the myristate.
  • 蛋白家族：
    CRISP family
  • 組織特異性：
    Highest expression in lung and peripheral leukocytes, and minor expression in liver and kidney.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18007

    OMIM: 607141

    KEGG: hsa:152007

    STRING: 9606.ENSP00000367196

    UniGene: Hs.493819



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