在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GJC1 Antibody, FITC conjugated

  • 中文名稱:
    GJC1兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA009458EC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GJC1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GJC1
  • 別名:
    GJC1; GJA7; Gap junction gamma-1 protein; Connexin-45; Cx45; Gap junction alpha-7 protein
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Gap junction gamma-1 protein (247-396AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
  • 基因功能參考文獻:
    1. our data highlighted the critical role of CX45 in reprogramming and may increase the cell division rate and result in an accelerated kinetics of iPSCs production. PMID: 28352086
    2. human Cx40/Cx45 and Cx43/Cx45 heterotypic gap junctions were investigated by recombinant expression in GJ deficient cells. PMID: 28760564
    3. Observations involving both N- and C-domains of CaM to interact with the Cx45 peptide differ from the embraced interaction with Cx50 from another connexin family PMID: 28963343
    4. Human deltoid muscle biopsies of 5 Chilean dysferlinopathy patients exhibited the presence of muscular connexins (Cx40.1, Cx43 and Cx45). PMID: 27229680
    5. Connexin45 has much more rapid gating kinetics than connexin43 PMID: 25401181
    6. Results found that the expression of Cx26 and Cx45 had no prognostic value but Cx43 was upregulated in tumour epithelia and membrane Cx43 expression was associated with short overall survival time. PMID: 24788723
    7. Gap junctional intercellular communication in human bladder smooth muscle cells and suburothelial myofibroblastsdepend of Cx43 rather than on Cx45. PMID: 21674053
    8. Our data suggest that GJA7 alterations have no or low genetic relevance in nonsyndromic hearing loss in populatins from Turkey, South Africa, United Kingdom, United States, and China. PMID: 21254920
    9. DNA hypermethylation of the promoter region of GJC1, encoding connexin45, is an important mechanism in silencing gene expression in colorectal cancer. PMID: 21406965
    10. Study shows that fusion of a V5/6-His tag (hexa moiety M r = 0.93 kDa) to the CT segment of Cx40, Cx43 and Cx45 does not prevent the cells from forming channels. PMID: 21424225
    11. connexin genes Gjd2 coding for mCx36, Gjc1 coding for mCx45 and Gja10 coding for mCx57 in the mouse, a subset of 4 connexin genes, including the unique GJA9 (Cx59) and GJA10 (Cx62), could be detected at least as transcript isoforms in the human retina. PMID: 20979653
    12. Results show that Cx40, Cx37, Cx43 and Cx45 were expressed within the glomeruli. PMID: 20530971
    13. Studies indicate that 21 different Cxs have been detected and they are generally named according to their approximate molecular mass in Kda, e.g. Cx32, Cx43 and Cx45. PMID: 19883623
    14. Data suggest that the dynamic changes of connexins 43, 40 and 45 during mouse cardiac development appear to be mirrored in the human. PMID: 12064615
    15. abnormal expression of connexin43 and connexin45 in nasopharynx tissues may be associated with cancerization and squamatization of human nasopharynx tissue PMID: 12452056
    16. mRNA levels of connexins in different sizes of luteinized normal and hyperstimulated follicles. PMID: 14667880
    17. The staining patterns for Cx45 rather were typified by granular cytoplasmic staining. PMID: 14766937
    18. Cx45 has a complex binding interaction with zonula occludens-1 (ZO-1) that involves either an extended carboxyl terminal domain or two distinct binding sites. PMID: 16463142
    19. Cx40/Cx45 junctions demonstrate electrical signal transfer asymmetry that can be modulated between unidirectional and bidirectional by small changes in the difference between holding potentials of the coupled cells. PMID: 17189315
    20. a cross-talk between CFTR and a variety of gap junction channels. Cytoskeletal scaffolding proteins and/or other intermediate cytoplasmic proteins are likely to play a role in CFTR-connexins interaction. PMID: 17546509

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
  • 蛋白家族:
    Connexin family, Gamma-type subfamily
  • 數據庫鏈接:

    HGNC: 4280

    OMIM: 608655

    KEGG: hsa:10052

    STRING: 9606.ENSP00000333193

    UniGene: Hs.712052



主站蜘蛛池模板: 欧美亚洲国产精品久久蜜芽| 国产69精品久久久久999小说| 波多野结衣在线观看一码| 少妇性俱乐部纵欲狂欢电影| 天天天天做夜夜夜夜做无码 | 免费网站看sm调教视频| 人人澡人人透人人爽| 狼色精品人妻在线视频免费 | 欧美成人一区二免费视频软件| 国产后入清纯学生妹| 成在线人av无码高潮喷水| 久久精品国产成人午夜福利| 亚洲a∨无码一区二区三区| 特级av毛片免费观看| 亚洲不卡av不卡一区二区| 大陆国产乱人伦| 亚洲精品亚洲人成在线下载 | 国产av综合影院| 国产传媒麻豆剧精品av国产 | 无码欧精品亚洲日韩一区| 欧美成va视频网站| 久久综合国产乱子伦精品免费| 精品偷拍一区二区三区在线看| 丁香五香天堂网| 国产成人亚洲综合精品| 欧美黑人巨大videos极品| 人妻体内射精一区二区三四| 非洲人与性动交ccoo| 超清无码av最大网站| 亚洲高清国产拍精品26u| 大肉大捧一进一出好爽视色大师| 亚洲综合无码精品一区二区三区 | 久久久久久久精品成人执小说一白| 2020精品国产a不卡片| 国产精品美女久久久网av| 玩弄漂亮少妇高潮白浆| 亚洲精品国偷自产在线99人热| 四虎影视在线影院在线观看免费视频| 欧美午夜精品久久久久久浪潮| 免费永久看黄神器无码软件| 在线观看国产丝袜控网站|