在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GIT2 Antibody, Biotin conjugated

  • 中文名稱:
    GIT2兔多克隆抗體, Biotin偶聯(lián)
  • 貨號:
    CSB-PA613489LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GIT2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    ARF GAP GIT2 antibody; ARF GTPase activating protein GIT2 antibody; ARF GTPase-activating protein GIT2 antibody; CAT 2 antibody; CAT-2 antibody; CAT2 antibody; Cool associated tyrosine phosphorylated protein 2 antibody; Cool interacting tyrosine phosphorylated protein 2 antibody; Cool-interacting tyrosine-phosphorylated protein 2 antibody; DKFZp686G01261 antibody; G protein coupled receptor kinase interacting ArfGAP 2 antibody; G protein coupled receptor kinase interactor 2 antibody; G protein-coupled receptor kinase-interactor 2 antibody; GIT 2 antibody; GIT2 antibody; GIT2_HUMAN antibody; GRK interacting protein 2 antibody; GRK-interacting protein 2 antibody; KIAA0148 antibody; MGC760 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human ARF GTPase-activating protein GIT2 protein (1-603AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    GTPase-activating protein for ADP ribosylation factor family members, including ARF1.
  • 基因功能參考文獻:
    1. our work identifies DOCK5 as a key regulator of epithelial invasion and metastasis, and demonstrates that suppression of DOCK5 by GIT2 represents a previously unappreciated mechanism for coordination of Rho and Rac GTPases. PMID: 27669437
    2. Short-term EGF stimulation if of lung tumor cells can increase the interaction between RUSC2 and GIT2, prolonged stimulation leads to a decrease of their interaction through activating Rab35. PMID: 27238570
    3. GIT2 plays an important role in MRE11/ATM/H2AX-mediated DNA damage responses. PMID: 25605334
    4. ADMA and L-arginine are substrates of human CAT2A, CAT2B, OCT2 and MATE1. Transport kinetics of CAT2A, CAT2B, and OCT2 indicate a low affinity, high capacity transport, which may be relevant for renal and hepatic elimination of ADMA or L-arginine PMID: 23864433
    5. Zeb1 is regulated by the Arf GTPase-activating protein (GAP) Git2. PMID: 23591815
    6. GIT2 protein is tightly associated with PIX family Rac1/Cdc42 guanine nucleotide exchange factors as a multimeric nexus capable of linking together important signaling molecules. PMID: 15212761
    7. The expression level of lymphocyte GRK might show the severity of CHF, and ACEI treatment could reduce the level of GRK in CHF patients. PMID: 16501306
    8. GTI proteins regulate cytoskeletal dynamics by feedback inhibition of Rac1, they participate in receptor internalization by regulating membrane trafficking between PMID: 16598076
    9. These results suggest that inactivation of GIT2 function is a required step for induction of cell motility and that GIT2 may be a target of oncogenic signaling pathways that regulate cell migration. PMID: 16628223
    10. Git2-short, weakly interacting with paxillin, functions in the regulation of Golgi organization, actin cytoskeletal organization, and subcellular localization of paxillin, important in integrin-mediated cell adhesion and intracellular signaling. PMID: 11251077

    顯示更多

    收起更多

  • 數(shù)據(jù)庫鏈接:

    HGNC: 4273

    OMIM: 608564

    KEGG: hsa:9815

    STRING: 9606.ENSP00000347464

    UniGene: Hs.434996



主站蜘蛛池模板: 亚洲精品无码专区在线观看| 激情五月综合色婷婷一区二区| 亚洲综合av在线在线播放| 情人伊人久久综合亚洲| 亚洲级αv无码毛片久久精品| 8x福利精品第一导航| 内射一区二区精品视频在线观看| 国产成人精品a视频免费福利| 国产深夜男女无套内射| 无码人妻精品中文字幕免费东京热 | 曰本女人与公拘交酡| 亚洲mv国产mv在线mv综合试看| 一区二区三区四区在线 | 欧洲| 曰本av中文字幕一区二区| 乱中年女人伦| 亚洲精品亚洲人成在线观看| 疯狂迎合进入强壮公的视频| 国产精品禁18久久久夂久 | 国产午国产午夜精华 免费| 成在人av抽搐高潮喷水流白浆| 亚洲a成人无码网站在线| 在线观看国产丝袜控网站| 国产一区二区三区免费观看在线 | 久久精品无码一区二区日韩av| 亚洲vav在线男人的天堂| 久久久久欧美精品观看| 少妇粗大进出白浆嘿嘿视频| 成人动漫在线观看| 久久三级中文欧大战字幕| 精品国产在天天在线观看| 女女互磨互喷水高潮les呻吟 | 国产国语老龄妇女a片| 欧美精品中文字幕亚洲专区| 日韩亚洲中字无码一区二区三区| 综合激情五月综合激情五月激情1| 成人欧美一区二区三区| 成年女人色毛片| 亚洲欧洲无码av不卡在线| 日韩人妻少妇一区二区| 国产中文字字幕乱码无限| 无码免费午夜福利看片|