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Your Good Partner in Biology Research

GID8 Antibody, Biotin conjugated

  • 中文名稱:
    GID8兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA882124LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GID8 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GID8
  • 別名:
    GID8 antibody; C20orf11 antibody; TWA1Glucose-induced degradation protein 8 homolog antibody; Two hybrid-associated protein 1 with RanBPM antibody; Twa1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Glucose-induced degradation protein 8 homolog protein (1-228AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation.
  • 基因功能參考文獻:
    1. The results identify Twa1 as a previously undescribed regulator of the Wnt pathway for promoting colorectal tumorigenesis by facilitating beta-catenin nuclear retention. PMID: 28829046
  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    GID8 family
  • 組織特異性:
    Up-regulated in colorectal cancer tissues (at protein level).
  • 數據庫鏈接:

    HGNC: 15857

    OMIM: 611625

    KEGG: hsa:54994

    STRING: 9606.ENSP00000266069

    UniGene: Hs.353013



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