在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GEMIN4 Antibody

  • 中文名稱:
    GEMIN4兔多克隆抗體
  • 貨號:
    CSB-PA009363LA01HU
  • 規格:
    ¥440
  • 圖片:
    • IHC image of CSB-PA009363LA01HU diluted at 1:400 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of A549 cells with CSB-PA009363LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GEMIN4 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GEMIN4
  • 別名:
    GEMIN4 antibody; Gem-associated protein 4 antibody; Gemin-4 antibody; Component of gems 4 antibody; p97 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Gem-associated protein 4 protein (741-848AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,GEMIN4 Antibody (CSB-PA009363LA01HU),的標記方式是Non-conjugated。對于GEMIN4 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA009363LB01HU GEMIN4 Antibody, HRP conjugated ELISA
    FITC CSB-PA009363LC01HU GEMIN4 Antibody, FITC conjugated
    Biotin CSB-PA009363LD01HU GEMIN4 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate. Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP.
  • 基因功能參考文獻:
    1. These findings indicate that GEMIN4 functions as a novel coregulator of the MR. PMID: 25555524
    2. the association between the GEMIN4 gene and the risk of prostate cancer PMID: 22506892
    3. zinc-finger proteins were identified as HCAP1-interacting proteins PMID: 12869526
    4. A haplotype of HCAP1 with minor alleles at 5 single nucleotide polymorphisms may be related to cancer susceptibility: its expression causes up-regulation of genes involved in cell growth and down-regulation of genes involved in apoptosis and DNA repair. PMID: 14603441
    5. A canonical nuclear import sequence in the N-terminus of Gemin4 was identified. PMID: 18675250

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Nucleus, nucleolus. Nucleus, gem. Note=Localized in subnuclear structures next to coiled bodies, called gems, which are highly enriched in spliceosomal snRNPs and in the nucleolus.
  • 數據庫鏈接:

    HGNC: 15717

    OMIM: 606969

    KEGG: hsa:50628

    STRING: 9606.ENSP00000321706

    UniGene: Hs.499620



主站蜘蛛池模板: 2020久久超碰国产精品最新| 欧美午夜精品一区二区三区电影| 亚洲综合色丁香婷婷六月图片| 欧洲亚洲1卡二卡三卡2021| 蜜臀久久99精品久久久久久小说| 国产乱人伦中文无无码视频试看 | 久久久久久av无码免费看大片| 亚洲国产成人第一天堂| 欧美做爰性生交视频| 97影院理论片手机在线观看 | 狠狠色婷婷久久综合频道毛片| 影音先锋女人aa鲁色资源| 亚洲性色av一区二区三区| 亚洲 欧美 影音先锋| 亚洲va韩国va欧美va| 精品国产乱码久久久久夜深人妻| 亚洲中文字幕日产无码成人片| 特级毛片全部免费播放| 成人亚洲性情网站www在线观看| 久久精品中文闷骚内射| 日本免费一区二区三区日本| 国产精品爽爽va吃奶在线观看| 欧美老人巨大xxxx做受| 天天躁日日摸久久久精品| 伊人久久大香线蕉综合5g| av无码免费岛国动作片不卡| 欧美高清在线精品一区| 国产丝袜无码一区二区视频| 国产一本一道久久香蕉| 国产av一区二区三区日韩| 亚洲人午夜射精精品日韩| 免费两性的视频网站 | 法国啄木乌av片在线播放| 免费无码作爱视频| 国产电影一区二区三区| 好男人社区资源| 超级碰97直线国产免费公开| 性饥渴少妇av无码毛片| av色综合久久天堂av色综合在| 人妻少妇乱子伦精品| 亚洲成a∧人片在线播放调教|