在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GDI1 Antibody, HRP conjugated

  • 中文名稱:
    GDI1兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA01229B0Rb
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GDI1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GDI1
  • 別名:
    1A antibody; FLJ41411 antibody; GDI-1 antibody; gdi1 antibody; GDIA_HUMAN antibody; GDIL antibody; GDP dissociation inhibitor 1 antibody; Guanosine diphosphate dissociation inhibitor 1 antibody; Mental retardation X-linked 41 antibody; Mental retardation X-linked 48 antibody; MRX41 antibody; MRX48 antibody; Oligophrenin 2 antibody; Oligophrenin-2 antibody; OPHN2 antibody; Protein XAP 4 antibody; Protein XAP-4 antibody; Protein XAP4 antibody; Rab GDI alpha antibody; Rab GDP dissociation inhibitor alpha antibody; RABGD1A antibody; RABGDIA antibody; XAP 4 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Rab GDP dissociation inhibitor alpha protein (35-170AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes.
  • 基因功能參考文獻:
    1. Data confirm isolated adrenocorticotropin deficiency (IAD) as autoimmune disease; RABGDIA (human, human recombinant, or rat) exhibits characteristics of autoantigen in anterior pituitary; patients with IAD exhibit autoantibodies against RABGDIA. PMID: 25346144
    2. Human oligodendrogliomas cells stably expressing mutant GDI1 showed altered cell proliferation. PMID: 25694352
    3. The results of this study identified RabGDI as a component of the switching mechanism that is required for commissural axons to change their response from attraction to repulsion at the intermediate target PMID: 23140504
    4. GDI1 mutations cause an unspecific phenotype characterized by cognitive deficits of variable degree in males, and to a lesser degree in female carriers. PMID: 22002931
    5. The mutations in this gene are common and do not seem to influence the gene expression so as to cause a change in phenotype. PMID: 21736009
    6. A model by which mutant PrP induces overexpression of GDI, activating a cytotoxic feedback loop that leads to protein accumulation in the secretory pathway. PMID: 19996123
    7. RhoGDI has a role in inactivating Rho GTPases with ExoS RhoGAP PMID: 15292224
    8. isoprenylcysteine carboxylmethyltransferase regulates Rac1 activity by controlling the interaction of Rac1 with RhoGDI through TNFA PMID: 15647276
    9. RhoGDI overexpression is associated with paclitaxel resistance in ovarian cancers PMID: 16596196
    10. The results of case-control analysis indicated that, no association between the rs11549300 polymorphisms of GDI1 and children NSMR (P >0.05), but its polymorphisms may be related to intelligence levels of children in Qinba region (P =0.03). PMID: 18487148
    11. GDI-1 is preferentially involved in insulin-stimulated glucose transporter 4 (GLUT4) translocation through facilitating Rab10 recycling. PMID: 19570034

    顯示更多

    收起更多

  • 相關疾病:
    Mental retardation, X-linked 41 (MRX41)
  • 亞細胞定位:
    Cytoplasm. Golgi apparatus, trans-Golgi network.
  • 蛋白家族:
    Rab GDI family
  • 組織特異性:
    Brain; predominant in neural and sensory tissues.
  • 數據庫鏈接:

    HGNC: 4226

    OMIM: 300104

    KEGG: hsa:2664

    STRING: 9606.ENSP00000394071

    UniGene: Hs.595950



主站蜘蛛池模板: 2021精品亚洲中文字幕| 亚洲三区在线观看内射后入| 青青青草国产线观| 男女啪啪抽搐高潮动态图| 国产黑色丝袜在线看片不卡顿| 亚洲中文字幕无码久久2017 | 欧美高潮喷水大叫| 一級特黃色毛片免費看| 人人超碰人人爱超碰国产| 美女张开腿让男人桶爽| 日韩精品无码免费专区网站| 无码精品人妻一区二区三区98| 国产乱人伦精品一区二区在线观看| 十八岁以下禁止观看黄下载链接| 亚洲小说图区综合在线| 秋霞国产精品一区二区| 7777奇米四色成人眼影| 国产午夜无码视频在线观看| 亚洲日本va午夜中文字幕久久| 国产放荡对白视频在线观看| 欧美黑人乱大交| 国产人妻人伦精品1国产| 久久天堂av综合合色蜜桃网| 一区二区在线欧美日韩中文| 久久国产欧美日韩精品| 无码午夜成人1000部免费视频| 久久国产精品2020免费| 任你躁在线精品免费| 久久久精品人妻久久影视| 精品无人区码一码二码三码区别| 久久天天躁狠狠躁夜夜爽| 国产精品18久久久久久vr| 成人无码www在线看免费 | 在线播放偷拍一区精品| 性久久久久久久| 最新69国产成人精品视频免费| 少妇被黑人4p到惨叫欧美人| 亚洲国产精品一区二区成人片| 又粗又黄又硬又爽的免费视频| 国产免费又色又爽又黄软件| 久久久久国产精品熟女影院|