在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GDI1 Antibody, HRP conjugated

  • 中文名稱:
    GDI1兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA01229B0Rb
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GDI1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GDI1
  • 別名:
    1A antibody; FLJ41411 antibody; GDI-1 antibody; gdi1 antibody; GDIA_HUMAN antibody; GDIL antibody; GDP dissociation inhibitor 1 antibody; Guanosine diphosphate dissociation inhibitor 1 antibody; Mental retardation X-linked 41 antibody; Mental retardation X-linked 48 antibody; MRX41 antibody; MRX48 antibody; Oligophrenin 2 antibody; Oligophrenin-2 antibody; OPHN2 antibody; Protein XAP 4 antibody; Protein XAP-4 antibody; Protein XAP4 antibody; Rab GDI alpha antibody; Rab GDP dissociation inhibitor alpha antibody; RABGD1A antibody; RABGDIA antibody; XAP 4 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Rab GDP dissociation inhibitor alpha protein (35-170AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes.
  • 基因功能參考文獻:
    1. Data confirm isolated adrenocorticotropin deficiency (IAD) as autoimmune disease; RABGDIA (human, human recombinant, or rat) exhibits characteristics of autoantigen in anterior pituitary; patients with IAD exhibit autoantibodies against RABGDIA. PMID: 25346144
    2. Human oligodendrogliomas cells stably expressing mutant GDI1 showed altered cell proliferation. PMID: 25694352
    3. The results of this study identified RabGDI as a component of the switching mechanism that is required for commissural axons to change their response from attraction to repulsion at the intermediate target PMID: 23140504
    4. GDI1 mutations cause an unspecific phenotype characterized by cognitive deficits of variable degree in males, and to a lesser degree in female carriers. PMID: 22002931
    5. The mutations in this gene are common and do not seem to influence the gene expression so as to cause a change in phenotype. PMID: 21736009
    6. A model by which mutant PrP induces overexpression of GDI, activating a cytotoxic feedback loop that leads to protein accumulation in the secretory pathway. PMID: 19996123
    7. RhoGDI has a role in inactivating Rho GTPases with ExoS RhoGAP PMID: 15292224
    8. isoprenylcysteine carboxylmethyltransferase regulates Rac1 activity by controlling the interaction of Rac1 with RhoGDI through TNFA PMID: 15647276
    9. RhoGDI overexpression is associated with paclitaxel resistance in ovarian cancers PMID: 16596196
    10. The results of case-control analysis indicated that, no association between the rs11549300 polymorphisms of GDI1 and children NSMR (P >0.05), but its polymorphisms may be related to intelligence levels of children in Qinba region (P =0.03). PMID: 18487148
    11. GDI-1 is preferentially involved in insulin-stimulated glucose transporter 4 (GLUT4) translocation through facilitating Rab10 recycling. PMID: 19570034

    顯示更多

    收起更多

  • 相關疾病:
    Mental retardation, X-linked 41 (MRX41)
  • 亞細胞定位:
    Cytoplasm. Golgi apparatus, trans-Golgi network.
  • 蛋白家族:
    Rab GDI family
  • 組織特異性:
    Brain; predominant in neural and sensory tissues.
  • 數據庫鏈接:

    HGNC: 4226

    OMIM: 300104

    KEGG: hsa:2664

    STRING: 9606.ENSP00000394071

    UniGene: Hs.595950



主站蜘蛛池模板: 上司揉捏人妻丰满双乳电影| 中文天堂在线资源www| 亚洲精品日韩一区二区小说| 国产啪精品视频网站免| 97夜夜澡人人爽人人| 国产日韩综合一区在线观看| 妺妺窝人体色www看人体| 极品少妇被啪到呻吟喷水| 久久婷婷激情综合色综合俺也去 | 国产日韩欧美亚欧在线观看| 狠狠色狠狠色综合日日五| 精品久久久久久| 性欧美老人牲交xxxxx视频| 久久综合九色综合97网| 久久精品私人影院免费看| 亚洲.欧美.在线视频| 97人妻天天摸天天爽天天 | 无码人妻丰满熟妇区bbbbxxxx| 免费国产黄网站在线观看| 一本久道高清无码视频| 亚洲日产av中文字幕无码偷拍| 韩国三级无码hd中文字幕| 国产精品 精品国内自产拍| 成人无码影片精品久久久| 韩国精品一区二区三区无码视频| 蜜桃av久久久一区二区三区麻豆| 天堂久久天堂av色综合| 色婷婷亚洲精品综合影院| 99久久久无码国产精品古装| 综合激情久久综合激情| 亚洲综合网站久久久| 免费观看的av毛片的网站| 狠狠热精品免费视频| a国产在线v的不卡视频| 亚洲日韩色在线影院性色| 狠狠亚洲狠狠欧洲2019| 加勒比久久综合网天天| 人妻精品国产一区二区| 1313午夜精品理论片| 欧美性xxxxx极品少妇直播| 97香蕉碰碰人妻国产欧美|