在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GATM Antibody

GATM Antibody

  • 中文名稱：
    GATM兔多克隆抗體
  • 貨號(hào)：
    CSB-PA009284GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    GATM
  • 別名：
    AGAT antibody; AT antibody; GATM antibody; GATM_HUMAN antibody; Glycine amidinotransferase antibody; Glycine amidinotransferase, mitochondrial antibody; L-arginine:glycine amidinotransferase antibody; mitochondrial antibody; Transamidinase antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human GATM
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis.
  • 基因功能參考文獻(xiàn)：
    1. Measurements of creatine and guanidinoacetate in plasma are recommended for the diagnosis of AGAT and GAMT deficiency.Definitive confirmation of the diagnosis requires DNA sequencing of the appropriate gene and (if molecular analysis is ambiguous) measurement of AGAT or GAMT enzyme activity or of CRTR-mediated transport . PMID: 28055022
    2. Results show the functional characterization of rare missense variants in GATM which cause GATM deficiency. Seven of them report 0% of wild-type GATM activity indicating a putative pathogenicity. PMID: 27233232
    3. AGAT deficiency is a treatable intellectual disability. PMID: 26490222
    4. Meta-analysis yielded a marginal, but null, association of GATM rs9806699 with statin-induced myopathy. PMID: 25863251
    5. Genome-wide association reveals that plasma homoarginine is strongly associated with single nucleotide polymorphisms in the AGAT gene. PMID: 24004504
    6. promiscuous activity of AGAT, a key enzyme in creatine synthesis, plays a pivotal role in homoarginine synthesis PMID: 23010440
    7. GATM sequencing revealed a homozygous single nucleotide insertion 1111_1112insA, producing a frame-shift at Met-371 and premature termination at codon 376. PMID: 20682460
    8. AGAT mRNA expression was significantly elevated in all heart failure patients and returned to normal levels after recovery, suggesting a specific response to heart failure involving elevated local creatine synthesis. PMID: 16820567

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Cerebral creatine deficiency syndrome 3 (CCDS3)
  • 亞細(xì)胞定位：
    [Isoform 1]: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Probably attached to the outer side of the inner membrane.; [Isoform 2]: Cytoplasm.
  • 蛋白家族：
    Amidinotransferase family
  • 組織特異性：
    Expressed in brain, heart, kidney, liver, lung, salivary gland and skeletal muscle tissue, with the highest expression in kidney. Biallelically expressed in placenta and fetal tissues.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 4175

    OMIM: 602360

    KEGG: hsa:2628

    STRING: 9606.ENSP00000379895

    UniGene: Hs.560354



主站蜘蛛池模板： 人妻综合专区第一页| 四虎国产精品永久在线| h无码动漫在线观看| 日本高清va在线播放| 亚洲一区二区三区中文字幕在线 | 国产露脸无套对白在线播放| 好吊妞无缓冲视频观看| 欧美成人精品一区二区综合a片| 50岁熟妇的呻吟声对白| 制服丝袜中文字幕在线| а√天堂资源官网在线资源| 久久伊99综合婷婷久久伊| 伊人精品成人久久综合97| 亚洲人成中文字幕在线观看| 国产后入清纯学生妹| 国产色青青视频在线观看撒| 色噜噜噜亚洲男人的天堂| 欧美成人一区二免费视频软件| www.-级毛片线天内射视视| 蜜色欲多人av久久无码| 亚洲а∨天堂男人色无码| 久久aaaa片一区二区| 精品噜噜噜噜久久久久久久久| 性xxxxx欧美极品少妇| 欧美日本精品一区二区三区| 熟妇女人妻丰满少妇中文字幕 | 久久三级中文欧大战字幕| 精品国产天堂综合一区在线| 人妻丰满被色诱中文字幕| 亚洲香蕉视频天天爽| 大狠狠大臿蕉香蕉大视频| 国产成人精品日本亚洲网站| 黑人粗长大战亚洲女| 伊人久久丁香色婷婷啪啪| a毛片终身免费观看网站| 久久躁狠狠躁夜夜av| 上司揉捏人妻丰满双乳电影| 国产精品久久久久久久伊一| 精精国产xxxx视频在线| 精品无码av无码专区| 久久99av无色码人妻蜜|