在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GATM Antibody

GATM Antibody

  • 中文名稱：
    GATM兔多克隆抗體
  • 貨號(hào)：
    CSB-PA009284GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    GATM
  • 別名：
    AGAT antibody; AT antibody; GATM antibody; GATM_HUMAN antibody; Glycine amidinotransferase antibody; Glycine amidinotransferase, mitochondrial antibody; L-arginine:glycine amidinotransferase antibody; mitochondrial antibody; Transamidinase antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human GATM
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis.
  • 基因功能參考文獻(xiàn)：
    1. Measurements of creatine and guanidinoacetate in plasma are recommended for the diagnosis of AGAT and GAMT deficiency.Definitive confirmation of the diagnosis requires DNA sequencing of the appropriate gene and (if molecular analysis is ambiguous) measurement of AGAT or GAMT enzyme activity or of CRTR-mediated transport . PMID: 28055022
    2. Results show the functional characterization of rare missense variants in GATM which cause GATM deficiency. Seven of them report 0% of wild-type GATM activity indicating a putative pathogenicity. PMID: 27233232
    3. AGAT deficiency is a treatable intellectual disability. PMID: 26490222
    4. Meta-analysis yielded a marginal, but null, association of GATM rs9806699 with statin-induced myopathy. PMID: 25863251
    5. Genome-wide association reveals that plasma homoarginine is strongly associated with single nucleotide polymorphisms in the AGAT gene. PMID: 24004504
    6. promiscuous activity of AGAT, a key enzyme in creatine synthesis, plays a pivotal role in homoarginine synthesis PMID: 23010440
    7. GATM sequencing revealed a homozygous single nucleotide insertion 1111_1112insA, producing a frame-shift at Met-371 and premature termination at codon 376. PMID: 20682460
    8. AGAT mRNA expression was significantly elevated in all heart failure patients and returned to normal levels after recovery, suggesting a specific response to heart failure involving elevated local creatine synthesis. PMID: 16820567

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Cerebral creatine deficiency syndrome 3 (CCDS3)
  • 亞細(xì)胞定位：
    [Isoform 1]: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Probably attached to the outer side of the inner membrane.; [Isoform 2]: Cytoplasm.
  • 蛋白家族：
    Amidinotransferase family
  • 組織特異性：
    Expressed in brain, heart, kidney, liver, lung, salivary gland and skeletal muscle tissue, with the highest expression in kidney. Biallelically expressed in placenta and fetal tissues.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 4175

    OMIM: 602360

    KEGG: hsa:2628

    STRING: 9606.ENSP00000379895

    UniGene: Hs.560354



主站蜘蛛池模板： 囯产精品一品二区三区| 久久久久99精品成人片试看 | 亚洲欧美日产综合在线| 亚洲欧美综合区自拍另类| 少妇高潮惨叫久久久久久| 天堂资源中文最新版在线一区| 992tv精品视频tv在线观看| 久久av高潮av无码av喷吹| 麻豆亚洲一区| 国产色诱视频在线观看| 亚洲国产精品无码久久久蜜芽| 欧美性潮喷xxxxx免费视频看| 57pao成人国产永久免费视频| 在线综合亚洲欧美日韩| 久久99av无色码人妻蜜| 激情综合一区二区三区| 西西人体做爰大胆gogo| 国产互换人妻hd| 日韩美女自卫慰黄网站| 伊人婷婷六月狠狠狠去| 无码精品人妻一区二区三区影院 | 午夜性色福利在线视频福利| 潮喷大喷水系列无码| 久久久国产打桩机| 国产日产欧产精品| 俺去啦俺来也五月天| 中文字幕亚洲综合久久菠萝蜜| 久久久久人妻精品一区蜜桃| 国产精品亚洲综合久久系列| 午夜福利免费0948视频| 超碰国产精品久久国产精品99| 综合三区后入内射国产馆| 18禁黄污无遮挡无码网站| 又粗又大又黄又爽的免费视频| 噜噜噜亚洲色成人网站| 99久久无色码中文字幕人妻蜜柚| 欧美专区另类专区在线视频| 国产又粗又猛又大爽又黄| 亚欧欧美人成视频在线| 日本边添边摸边做边爱边| 日韩人妻无码一区二区三区|