在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FZD9 Antibody

  • 中文名稱:
    FZD9兔多克隆抗體
  • 貨號:
    CSB-PA060242
  • 規格:
    ¥1090
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    FZD9; FZD3; Frizzled-9; Fz-9; hFz9; FzE6; CD antigen CD349
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the N-terminal region of Human Frizzled-9.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Receptor for WNT2 that is coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. Plays a role in neuromuscular junction (NMJ) assembly by negatively regulating the clustering of acetylcholine receptors (AChR) through the beta-catenin canonical signaling pathway. May play a role in neural progenitor cells (NPCs) viability through the beta-catenin canonical signaling pathway by negatively regulating cell cycle arrest leading to inhibition of neuron apoptotic process. During hippocampal development, regulates neuroblast proliferation and apoptotic cell death. Controls bone formation through non canonical Wnt signaling mediated via ISG15. Positively regulates bone regeneration through non canonical Wnt signaling.
  • 基因功能參考文獻:
    1. the present study indicated that the methylation profile of the FZD9 gene corresponded to that of a candidate tumorsuppressor gene in acute myeloid leukemia. PMID: 27314612
    2. The presence of nanog, Oct-4, SSEA-1, and SSEA-4 suggests that periodontal ligament mesenchymal stem cells are less differentiated than bone marrow-derived MSCs, and the frizzled-9/Wnt pathway is important in proliferation and differentiation. PMID: 20458727
    3. The activity of the Sprouty4 promoter is increased by Wnt7A/Fzd9 signaling through peroxisome proliferator-activated receptor gamma in lung cancer cells. PMID: 20501643
    4. The presence of nanog, Oct-4, SSEA-1, and SSEA-4 suggests that periodontal ligament mesenchymal stem cells are less differentiated than bone marrow-derived MSCs, and that the frizzled-9/Wnt pathway is important in proliferation and differentiation. PMID: 20458727
    5. transfection of Fzd-9 into a Wnt-7a-insensitive NSCLC cell line established Wnt-7a sensitivity PMID: 15705594
    6. Aberrant DNA methylation of frizzled 9 protein is associated with myelodysplastic syndrome progression to acute myeloid leukemia. PMID: 18832655
    7. SiRNA of frizzled-9 suppresses proliferation and motility of hepatoma cells. PMID: 19724923

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor Fz/Smo family
  • 組織特異性:
    Expressed predominantly in adult and fetal brain, testis, eye, skeletal muscle and kidney. Moderately expressed in pancreas, thyroid, adrenal cortex, small intestine and stomach. Detected in fetal liver and kidney. Expressed in neural progenitor cells.
  • 數據庫鏈接:

    HGNC: 4047

    OMIM: 601766

    KEGG: hsa:8326

    STRING: 9606.ENSP00000345785

    UniGene: Hs.647029



主站蜘蛛池模板: 第一亚洲中文久久精品无码| 免费无码午夜理论电影| 日本19禁啪啪吃奶大尺度| 精品一区二区成人精品| 久久精品人妻中文系列| 热99re久久精品这里都是精品| 亚洲乱码国产一区三区| 美女张开腿让男人桶爽| 大陆精大陆国产国语精品 | 肉大捧一进一出免费视频| 欧美人与动牲交a欧美| 久久99热这里只有精品国产| 人人玩人人添人人澡欧美| 中文字幕久久精品无码| 国产日韩在线视看第一页 | 无码国模国产在线观看| 中文字幕爆乳julia女教师| 少妇三级全黄| 99re6热视频这里只精品首页| 小小拗女性bbwxxxx国产| 国产福利永久在线视频无毒不卡| 一本色综合亚洲精品蜜桃冫| 激情内射亚洲一区二区三区爱妻| 国产av麻豆mag剧集| 午夜dj高清免费观看视频| 精品国产一区二区三区国产区| 蜜桃少妇av久久久久久久| 亚洲 欧美 变态 另类 综合| 国产女主播白浆在线观看 | 国产av一区二区三区传媒| 色播亚洲视频在线观看| 制服视频在线一区二区| 人妻少妇久久精品电影| 14萝自慰专用网站| 无码无遮挡又大又爽又黄的视频| 四虎影视精品永久在线观看| 日韩高清在线亚洲专区小说| 国产偷国产偷亚洲清高app| 国产精品精华液网站| 人人鲁人人莫人人爱精品| 欧美综合自拍亚洲综合区|