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  4. FUZ Antibody, FITC conjugated

FUZ Antibody, FITC conjugated

  • 中文名稱：
    FUZ兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA883593LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) FUZ Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    FUZ
  • 別名：
    FLJ22688 antibody; fuz antibody; FUZZY_HUMAN antibody; Fy antibody; Protein fuzzy homolog antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Protein fuzzy homolog protein (280-404AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Probable planar cell polarity effector involved in cilium biogenesis. May regulate protein and membrane transport to the cilium. Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies. May regulate the morphogenesis of hair follicles which depends on functional primary cilia.
  • 基因功能參考文獻：
    1. results in vitro show that FUZ is responsible for non-small-cell lung cancer (NSCLC) progression and metastasis, suggesting that FUZ can be a potential therapeutic target for NSCLC. PMID: 29421438
    2. Data propose that mutations in Fuzzy may account for a subset of neural tube defects in humans. PMID: 21840926
  • 亞細胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    Fuzzy family
  • 數據庫鏈接：

    HGNC: 26219

    OMIM: 610622

    KEGG: hsa:80199

    STRING: 9606.ENSP00000313309

    UniGene: Hs.288800



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