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  4. FSD1 Antibody, Biotin conjugated

FSD1 Antibody, Biotin conjugated

  • 中文名稱：
    FSD1兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA861136LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) FSD1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    FSD1
  • 別名：
    Fibronectin type 3 and SPRY (spla; ryanodine) domain containing (with coiled-coil motif) 1 antibody; Fibronectin type 3 and SPRY domain containing 1 antibody; Fibronectin type III and SPRY domain containing 1 antibody; Fibronectin type III and SPRY domain-containing protein 1 antibody; Fibronectin type III and SPRY domains containing protein 1 antibody; FSD1 antibody; FSD1_HUMAN antibody; GLFND antibody; MGC3213 antibody; MGC58341 antibody; Microtubule-associated protein GLFND antibody; MID1-related protein 1 antibody; midline 1-related protein 1 antibody; MIR1 antibody; VLP27 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Fibronectin type III and SPRY domain-containing protein 1 protein (251-370AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May be involved in microtubule organization and stabilization.
  • 基因功能參考文獻：
    1. Overexpression of miR-1 mimics significantly decreased tumor glycolysis, including lactate production and glucose uptake, and cell proliferation, and these effects were reversed by ectopic expression of Smad3. PMID: 28471448
    2. These regulatory mechanisms of miR-1 expression could help us to understand the functions of altered miR-1 expression. PMID: 27923712
    3. Taken together, our findings established a tumor suppressive role for miR-1 in the progression of ccRCC by targeting CDK4, CDK6, Caprin1 and Slug and suggested miR-1 can be served as a novel potential therapeutic target for ccRCC. PMID: 26036633
    4. Data report the identification of MIR1, a protein with microtubule-binding activity which is located at the centrosome and is related to MID1/midin. [MIR1] PMID: 12154070
  • 亞細胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm. Cleavage furrow. Note=Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associates with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle.
  • 組織特異性：
    Highly expressed in brain tissues, including cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Lower expression in spinal chord.
  • 數據庫鏈接：

    HGNC: 13745

    OMIM: 609828

    KEGG: hsa:79187

    STRING: 9606.ENSP00000221856

    UniGene: Hs.28144



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