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  4. FOXL1 Antibody

FOXL1 Antibody

  • 中文名稱：
    FOXL1兔多克隆抗體
  • 貨號：
    CSB-PA002568
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of A549 cells using FoxL1 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    FOXL1
  • 別名：
    FKH 6 antibody; FKH6 antibody; FKHL 11 antibody; FKHL11 antibody; Forkhead (Drosophila) like 11 antibody; Forkhead box L1 antibody; Forkhead box protein L1 antibody; Forkhead related protein FKHL11 antibody; Forkhead related transcription factor 7 antibody; Forkhead-related protein FKHL11 antibody; Forkhead-related transcription factor 7 antibody; FOX L1 antibody; FOXL 1 antibody; Foxl1 antibody; FOXL1_HUMAN antibody; FREAC 7 antibody; FREAC-7 antibody; FREAC7 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Monkey
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human FoxL1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 AND GLI3 transcription factors.
  • 基因功能參考文獻：
    1. FOXL1 inhibited the proliferation, invasion, and migration of breast cancer.FOXL1 expression was reduced in breast cancer. PMID: 27938507
    2. our findings provide evidence that FOXL1 might serve as a candidate tumor suppressor and a potential prognostic biomarker for gastric cancer PMID: 26960689
    3. the downregulation of FOXL1 expression was associated with osteosarcoma cell growth. Restoration of FOXL1 gene expression by gene therapy may have a therapeutic potential for patients with osteosarcoma PMID: 26062977
    4. dysregulated FOXL1 is involved in tumorigenesis and progression of gallbladder cancer. PMID: 25010679
    5. results suggest that Foxl1 plays an inhibitory role in renal tumor progression. PMID: 24427331
    6. Lower FOXL1 expression is correlated with metastasis and advanced pathologic stage of pancreatic cancer. PMID: 23801748
    7. two novel de novo mutations in rare patients inherited gene variants in FOXL1. PMID: 21457232
    8. FUS-CREB3L2/L1-positive sarcomas show a specific gene expression profile with upregulation of CD24 and FOXL1. PMID: 21536545

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  • 亞細胞定位：
    Nucleus.
  • 數據庫鏈接：

    HGNC: 3817

    OMIM: 603252

    KEGG: hsa:2300

    STRING: 9606.ENSP00000326272

    UniGene: Hs.533830



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