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FOXI1 Antibody

  • 中文名稱:
    FOXI1兔多克隆抗體
  • 貨號(hào):
    CSB-PA008296
  • 規(guī)格:
    ¥1090
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    FOXI1
  • 別名:
    FKH10 antibody; FKHL10 antibody; Forkhead (Drosophila) like 10 antibody; Forkhead box I1 antibody; Forkhead box protein I1 antibody; Forkhead like 10 antibody; Forkhead related activator 6 antibody; Forkhead related transcription factor 6 antibody; Forkhead-related protein FKHL10 antibody; Forkhead-related transcription factor 6 antibody; FOXI1 antibody; FOXI1_HUMAN antibody; FREAC 6 antibody; FREAC-6 antibody; FREAC6 antibody; Hepatocyte nuclear factor 3 forkhead homolog 3 antibody; HFH 3 antibody; HFH-3 antibody; HFH3 antibody; HNF 3/fork head homolog 3 antibody; HNF-3 fork-head homolog 3 antibody; HNF-3/fork-head homolog 3 antibody; Human HNF-3 fork-head homolog-3 HFH-3 mRNA complete cds antibody; MGC34197 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human FoxI1.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules.
  • 基因功能參考文獻(xiàn):
    1. study reveals that Foxi1/miR-491-5p/Wnt3a/beta-catenin signaling is critical in the progression of GC. Targeting the pathway described in this study may open up new prospects to restrict the progression of gastric cancer PMID: 28358374
    2. We found no evidence for a significant association between mutations of KCNJ10 and FOXI1 with SLC26A4 in Pendred syndrome/enlarged vestibular aqueducts. PMID: 23965030
    3. No FOXI1 mutations were present in bilateral deafness patients with inner ear malformation. PMID: 22412181
    4. SLC26A4, FOXI1 and KCNJ10 are not major determinants in unilateral deafness and enlarged vestibular aqueduct PMID: 20621367
    5. C/EBP alpha and HNF-3 gamma cooperatively regulate CYP3A4 expression in hepatic cells by a mechanism that probably involves chromatin remodeling. PMID: 12695546
    6. Data suggestthat Foxi1 is necessary for expression of at least four subunits in three different epithelia and most likely is a major determinant for proper assembly of a functional vacuolar H(+)-ATPase complex at these locations. PMID: 19214237

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  • 亞細(xì)胞定位:
    Nucleus.
  • 組織特異性:
    Expressed in kidney.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 3815

    OMIM: 601093

    KEGG: hsa:2299

    STRING: 9606.ENSP00000304286

    UniGene: Hs.87236



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