在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FOXF2 Antibody, FITC conjugated

  • 中文名稱:
    FOXF2兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA623661LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) FOXF2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    FOXF2
  • 別名:
    FOXF2 antibody; FKHL6 antibody; FREAC2Forkhead box protein F2 antibody; Forkhead-related activator 2 antibody; FREAC-2 antibody; Forkhead-related protein FKHL6 antibody; Forkhead-related transcription factor 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Forkhead box protein F2 protein (226-364AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Probable transcription activator for a number of lung-specific genes. Mediates up-regulation of the E3 ligase IRF2BPL and drives ubiquitination and degradation of CTNNB1.
  • 基因功能參考文獻:
    1. FOXF2 rs1711972 AA genotype is associated with poor response to therapy in Non-small Cell Lung Cancer. PMID: 28766235
    2. miR130a can regulate FOXF2 and function as an oncogene in colorectal cancer. PMID: 28849155
    3. FOXF2 deficiency induced mesenchymal-epithelial transition (MET) in Huh7 cell which might facilitate the colonization of circulating tumor cells and the formation of metastasis. PMID: 28582850
    4. Cox proportional hazards regression model was used to evaluate the predictive value of FOXF2 mRNA level in non-small cell lung cancer patients PMID: 27487137
    5. FOXF2 has a dual role in breast tumorigenesis and functions as either a tumor suppressor or an oncogene depending on the breast tumor subtype. PMID: 27377963
    6. MAZ/FOXF2 axis can promote the proliferation of basal like breast cancer cells and suppress disease progression. PMID: 28577976
    7. direct targeting of Foxf2 by Shh signaling drives cranial neural crest cell mesenchyme proliferation during upper lip morphogenesis, and disruption of this sequence results in cleft lip. PMID: 28506991
    8. Common variants near FOXF2 that are associated with increased stroke susceptibility. PMID: 27068588
    9. No correlation was found between FOXF2 promoter methylation and other clinic pathological parameters (age, gender, differentiation, lymph node metastasis, stage, cutting edge, vascular invasion, smoking behavior, and drinking history) in esophageal squamous cell carcinoma. PMID: 28222662
    10. Loss of FOXF2 Expression is associated with Hepatocellular Carcinoma. PMID: 25824262
    11. results provided statistical evidence of linkage and association between FOXF2 and nonsyndromic cleft lip with or without cleft palate. PMID: 26278207
    12. The miR-200 family and the miR-183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers. PMID: 25798833
    13. MiR-182-induced downregulation of FoxF2. PMID: 25738520
    14. Subtype-specific expression and function of FOXF2 in breast cancer cells are regulated through the combined effects of DNA methylation and SP1 transcriptional regulation. PMID: 26070560
    15. Foxf2 inactivation in adults resulted in blood-brain barrier breakdown, endothelial thickening, and increased trans-endothelial vesicular transport PMID: 26120030
    16. decreased FOXF2 expression indicates the early-onset metastasis and poor prognosis for patients with histological grade II and triple-negative breast cancer. PMID: 23620774
    17. MicroRNA-182-5p promotes cell invasion and proliferation by down regulating FOXF2, RECK and MTSS1 genes in human prostate cancer. PMID: 23383207
    18. 2 unique DNA sequence alterations could have affected FOXF2 on the mRNA or protein level thus contributing to the observed disturbances in genital and palate development PMID: 19276632
    19. The distinct expression pattern of FOXF2 in the prostate, its effect on expression of signaling, and its opposing role in the TGFbeta3 pathway, suggests a role for FOXF2 in prostate homeostasis and stroma-epithelial interactions PMID: 19562724

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 組織特異性:
    Lung and placenta. Predominantly expressed in gastrointestinal tract including stomach.
  • 數據庫鏈接:

    HGNC: 3810

    OMIM: 603250

    KEGG: hsa:2295

    STRING: 9606.ENSP00000259806

    UniGene: Hs.484423



主站蜘蛛池模板: 色噜噜狠狠成人中文综合| 国产高清自产拍av在线 | 国产精品美女久久久久久| 久久综合给合久久狠狠狠97色69| 极品美女在线观看免费直播| 国产国产久热这里只有精品| 色偷偷人人澡久久超碰97| h无码精品3d动漫在线观看| 免费无遮挡无码视频在线观看| 国产亚洲精品久久久久久久| 国产美女在线精品免费观看| 日本丰满熟妇videossex| 黄网站色视频免费观看| 免费看小12萝裸体视频国产| 日韩好精品视频你懂的| 无码aⅴ精品一区二区三区| 国内精品免费久久久久电影院 | 欧美黑人巨大xxxxx视频| 日本不卡一区| 天堂网在线最新版www资源网| 久久精品2021国产| 免费现黄频在线观看国产| 成人免费播放视频777777| 国产天堂亚洲国产碰碰| 在线播放无码高潮的视频| 精品无码av一区二区三区| 久久精品香蕉绿巨人登场| 影视av久久久噜噜噜噜噜三级| 三个男吃我奶头一边一个视频| 牲欲强的熟妇农村老妇女视频| 色www永久免费视频首页| 无码人妻一区二区三区免费n鬼逝 好爽好湿好硬好大免费视频 | 97精品尹人久久大香线蕉| 中文字幕久久熟女人妻av免费| 亚洲欧美日韩成人一区| 任你干视频精品播放| 偷自拍亚洲视频在线观看99| 国产精品久久久久久人妻精品| 久久人搡人人玩人妻精品首页| 色多多成视频人在线观看| 成熟老妇女毛茸茸的做性|