在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FOSB Antibody, HRP conjugated

  • 中文名稱:
    FOSB兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA008791LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) FOSB Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Activator protein 1 antibody; AP 1 antibody; DKFZp686C0818 antibody; FBJ murine osteosarcoma viral oncogene homolog B antibody; fosB antibody; FOSB_HUMAN antibody; G0/G1 switch regulatory protein 3 antibody; G0S3 antibody; GOS 3 antibody; GOS B antibody; GOS3 antibody; GOSB antibody; MGC42291 antibody; Oncogene FOS B antibody; Oncogene FOSB antibody; Protein fos B antibody; Protein fosB antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Protein fosB protein (1-41AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    FosB interacts with Jun proteins enhancing their DNA binding activity.
  • 基因功能參考文獻:
    1. miR-144-3p plays an important role in pancreatic cancer cell proliferation, migration, and invasion by targeting FOSB PMID: 28653602
    2. FOSB immunohistochemistry is sensitive in the diagnosis of angiolymphoid hyperplasia with eosinophilia, and allows differentiation from its histological mimics PMID: 29527734
    3. FOSB overexpression results in TNBC cell death, whereas inhibition of calcium signaling eliminates FOSB induction and blocks TP4-induced TNBC cell death PMID: 27248170
    4. results shows the involvement of Spry2 in regulation of FosB and Runx2 genes, MAPK signaling and proliferation of mesenchymal stem cells. PMID: 28387432
    5. the mechanism underlying redox-regulation of AP-1 Fos/Jun transcription factors and provide structural insight for therapeutic interventions targeting AP-1 proteins. PMID: 28981703
    6. The NFATc3 first induced the expression of its interaction partner FosB before forming the heterodimeric NFATc3-FosB transcription factor complex, which bound the proximal AP-1 site in the TF gene promoter and activated TF expression. PMID: 28724635
    7. FosB expression in the prefrontal cortex and hippocampus of the cocaine addicted and depression patients PMID: 27494187
    8. FOSB is a highly sensitive and diagnostically useful marker for pseudomyogenic hemangioendothelioma. PMID: 28009608
    9. our findings show that DeltaFosB increases the expression of MMP-9 and exhibits a significantly high survival and proliferation in MCF-7 cells. PMID: 26608367
    10. Diffuse and strong FOSB expression was specific for pseudomyogenic hemangioendothelioma in the current series and FOSB immunohistochemistry is an effective tool for differentiating between PHE and its histological mimics. PMID: 27515856
    11. Our results using a number of approaches, such as promoter reporter assay, FosB knock down and Chip assay, suggest that the expression of miR-22 is regulated transcriptionally by FosB. PMID: 27889568
    12. These results suggest that SETDB1- mediated FosB expression is a common molecular phenomenon, and might be a novel pathway responsible for the increase in cell proliferation that frequently occurs during anticancer drug therapy. PMID: 26949019
    13. studies of FosB are providing new insight into the molecular basis of depression and antidepressant action. PMID: 25446562
    14. The abnormalities were screened by FISH in 44 epithelioid hemangioma (EH) from different locations with seven additional EH revealing FOSB gene rearrangements, all except one being fused to ZFP36. PMID: 25043949
    15. This study describing the expres-sion pattern of FosB/ FosB immunoreactivity inpost mortem basal ganglia sections from Parkinson disease patients. PMID: 23933656
    16. Pseudomyogenic haemangioendothelioma consistently displays a SERPINE1-FOSB fusion gene, resulting from a translocation between chromosomes 7 and 19. PMID: 24374978
    17. Data indicate a significant correlation in miR-181b, FOS and miR-21 expression glioma tissues. PMID: 23810250
    18. Report Fos-B expression in skin keratinocytes/fibroblasts and keloid fibroblasts exposed to genistein. PMID: 23614275
    19. AP-1 protein induction during monopoiesis favors C/EBP: AP-1 heterodimers over C/EBP homodimerization and stimulates FosB transcription. PMID: 21543584
    20. Induction of a DeltaFOSB mediated transcriptional pattern in the prefrontal cortex is opposite to the down-regulation observed in the nucleus accumbens in patients with major depressive disorder PMID: 21616539
    21. Findings indicate that neurobehavioral stress leads to FosB-driven increases in IL8, which is associated with increased tumor growth and metastases. PMID: 20826776
    22. transcription factor FosB/activating protein-1 (AP-1) activation is a prominent downstream signal of the extracellular nucleotide receptor P2RX7 in monocytic and osteoblastic cells PMID: 20813842
    23. RGS16 and FosB are underexpressed in pancreatic cancer with lymph node metastasis and associated with reduced survival PMID: 20571966
    24. demonstrated that a functional AP-1 site mediates MMP-2 transcription in cardiac cells through the binding of distinctive Fra1-JunB and FosB-JunB heterodimers. The synthesis of MMP-2 is considered to be independent of the AP-1 transcriptional complex PMID: 12371906
    25. AP-1 (c-Jun & FosB) binds to a site in the 5' untranslated region of the CD95L gene. Transdominant negative Jun mutants reduce CD95L promoter activity. FosB dimerized with c-Jun has an important role in TCR/CD3-mediated activation-induced cell death. PMID: 12618758
    26. In hepatoma-associated anorexia-cachexia FpsB was induced in several brain areas of thes forebrain. PMID: 15926923
    27. activation of protein kinase A elicits an immediate response through induction of genes such as ID2 and FosB, followed by sustained secretion of bone-related cytokines such as BMP-2, IGF-1, and IL-11 PMID: 18490653
    28. DeltaFosB was able to trigger partial Pref-1-mediated de-differentiation of adipocytes, which also retained their adipocytic cell phenotype. PMID: 18491952
    29. An IFN-gamma-mediated homeostatic loop limits the potential for tissue damage associated with inflammation and identifies transcriptional factor AP-1 that regulates matrix metalloproteinase expression in myeloid cells in inflammatory settings. PMID: 18802113
    30. MicroRNA-101, which is aberrantly expressed in hepatocellular carcinoma, could repress the expression of the FOS oncogene. PMID: 19133651
    31. FosB is induced in PMA treated K562 cells in a sustained manner and forms an active AP-1 protein-DNA complex. Down-regulation of FosB with specific shRNAs inhibited the induction of CD41, a specific cell surface marker of megakaryocytes. PMID: 19381435
    32. Results suggest that in addition to clinically prognostic factors, FOS-B expression has a debatable impact on patient survival. PMID: 19795327

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    BZIP family, Fos subfamily
  • 數據庫鏈接:

    HGNC: 3797

    OMIM: 164772

    KEGG: hsa:2354

    STRING: 9606.ENSP00000245919

    UniGene: Hs.590958



主站蜘蛛池模板: 国产av麻豆天堂亚洲国产av刚刚碰| 欧美又大又色又爽aaaa片| 色多多性虎精品无码av| 亚洲欧洲日产国码在线| 99精品丰满人妻无码a片| 亚洲国产成人久久综合一区77 | 欧美潮喷少妇100| 国产 | 久你欧洲野花视频欧洲1| 国产免费视频| av无码国产在线观看岛国| 国内免费视频成人精品| 亚洲欧美成aⅴ人在线观看| 国产伦精品一区二区三区免费迷| 97影院在线午夜| 国产美女a做受大片观看| 国产成+人欧美+综合在线观看| 在教室伦流澡到高潮hgl视频| 亚洲日韩精品欧美一区二区| 无套熟女av呻吟在线观看| 亚洲 小说 欧美 另类 社区| 色婷婷综合久色aⅴ五区最新| 麻豆精品导航| 变态 另类 欧美 大码 日韩| 奇米四色7777中文字幕| 亚洲精品少妇高清30p| 成人亚洲性情网站www在线观看| 欧美人与动人物牲交免费观看久久| 伊人久久大香线蕉av波多野结衣| 特级毛片全部免费播放| 精品丰满人妻无套内射| 人妻少妇一区二区三区| 亚洲经典国产精华液单品榜| 国产高清在线精品一区二区三区| 自慰无码一区二区三区| www国产精品内射| 亚洲一区波多野结衣在线| 欧美z0zo人禽交免费观看99| 美女视频黄是免费| 亚洲综合色婷婷七月丁香| 欧美老妇乱辈通奷| 无码一区二区|