在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FOLR2 Antibody, HRP conjugated

  • 中文名稱:
    FOLR2兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA008786LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) FOLR2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    beta hFR antibody; FBP antibody; FBP/PL 1 antibody; FBP2 antibody; fetal/placental antibody; folate receptor 2 (fetal) antibody; Folate receptor 2 antibody; Folate receptor antibody; Folate receptor beta antibody; Folate receptor; fetal/placental antibody; Folbp 2 antibody; Folbp2 antibody; Folr2 antibody; FOLR2_HUMAN antibody; FR beta antibody; FR P3 antibody; FR-beta antibody; Placental folate binding protein antibody; Placental folate-binding protein antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Folate receptor beta protein (35-167AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.
  • 基因功能參考文獻:
    1. Folate receptor beta as a novel CD11b/CD18 regulator for trafficking and homing of a subset of macrophages on collagen. PMID: 27534550
    2. FR-beta expression was low or absent in the majority of ovarian, breast and colorectal tumor samples. PMID: 26248049
    3. FR-beta is uniquely expressed on this proinflammatory subpopulation offers a new strategy to suppress migration of inflammatory monocytes into sites of inflammation. PMID: 25015955
    4. High FOLR2 mRNA expression is associated with uraemic patients on hemodialysis. PMID: 23439585
    5. severe pre-eclampsia is associated with decreased placental expression of FR-beta and a reduction in the number of fetal macrophages (Hofbauer cells) PMID: 23480364
    6. Expression of folate receptor-beta on activated macrophages holds a promising potential for early diagnosis of atherosclerosis. (Review) PMID: 22094710
    7. High Folate Receptor beta expressing tumor-associated macrophages are associated with pancreatic cancer. PMID: 22350599
    8. Functional FR-beta present on osteoarthritis synovial macrophages provides a potential tool for the diagnosis and treatment of this disease. PMID: 22211358
    9. study describes that functional FRbeta is specifically expressed by M-CSF-polarized (M2) macrophages as well as by ex vivo isolated tumor-associated macrophages, and that tumors induce its expression in an M-CSF-dependent manner PMID: 19951991
    10. FR-beta gene is a target for multiple coordinate actions of nuclear receptors for ATRA directly and indirectly acting on a transcriptional complex containing activating Sp1/ets and inhibitory AP-1 proteins. PMID: 12543860

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Lipid-anchor, GPI-anchor. Secreted.
  • 蛋白家族:
    Folate receptor family
  • 組織特異性:
    Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues.
  • 數據庫鏈接:

    HGNC: 3793

    OMIM: 136425

    KEGG: hsa:2350

    STRING: 9606.ENSP00000298223

    UniGene: Hs.433159



主站蜘蛛池模板: 久久久久久九九99精品| 精选国产av精选一区二区三区| 天天爽夜夜爽人人爽| 亚洲欧洲免费无码| 忍着娇喘人妻被中出中文字幕| 中文字幕av无码人妻| 波多野结衣乳巨码无在线| 久久精品99国产国产精| 夜色福利院在线观看免费| 国产精品久久久久久tv| 少妇人妻在线视频| 亚洲日韩乱码久久久久久| 国产精品有码无码av在线播放 | 欧美粗大猛烈老熟妇| 毛片免费观看天天干天天爽| 免费国产线观看免费观看| 国产熟妇久久777777| 俄罗斯大荫蒂女人毛茸茸| 天天综合网亚在线| 色 综合 欧美 亚洲 国产| 瑜伽裤国产一区二区三区| 日本高清www午色夜在线视频| 国产色情又大又粗又黄的电影| 欧美老妇与禽交| 国产精品福利自产拍在线观看| 日本一道一区二区视频| 五月天精品视频在线观看| 强奷人妻日本中文字幕| 亚洲日产av中文字幕无码偷拍| 2018高清国产一区二区三区| 香港aa三级久久三级| 亚洲最大成人网色| 成人影院永久免费观看网址| 午夜福利理论片高清在线观看| 老司机亚洲精品影院无码| 成在人线av无码免费高潮喷水| 色综合伊人色综合网站无码| 亚洲男人av香蕉爽爽爽爽| 在线亚洲日产一区二区| 少妇无码av无码去区钱| 看免费真人视频网站|