FNTA Antibody
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中文名稱：FNTA兔多克隆抗體
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貨號：CSB-PA008777GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：FNTA
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別名：CAAX farnesyltransferase alpha subunit antibody; CAAX farnesyltransferase subunit alpha antibody; EC 2.5.1.58 antibody; EC 2.5.1.59 antibody; Farnesyl protein transferase alpha subunit antibody; Farnesyltransferase CAAX box alpha antibody; Farnesyltransferase; CAAX box; alpha antibody; Fnta antibody; FNTA_HUMAN antibody; FPTA antibody; FTase alpha antibody; FTase-alpha antibody; GGTase I alpha antibody; GGTase-I-alpha antibody; MGC99680 antibody; OTTHUMP00000229206 antibody; OTTHUMP00000229262 antibody; PGGT1A antibody; Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit antibody; Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha antibody; Protein prenyltransferase alpha subunit repeat containing 2 antibody; PTAR2 antibody; Ras proteins prenyltransferase alpha antibody; Ras proteins prenyltransferase subunit alpha antibody; Type I protein geranyl geranyltransferase alpha subunit antibody; Type I protein geranyl-geranyltransferase subunit alpha antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human FNTA
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.
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基因功能參考文獻：
- These findings collectively suggest that the combination of farnesyltransferase inhibitors and gamma-secretase inhibitors is a promising therapeutic strategy for glioblastoma through selectively targeting the cancer stem cell subpopulation. PMID: 29198824
- Exploring the putative self-binding property of the human farnesyltransferase alpha-subunit PMID: 28948621
- our findings identify Geranylgeranyl transferase 1 as a key regulator of human airway smooth muscle cell viability PMID: 22160308
- Results suggest that all peptide substrates adopt a common binding mode in the protein farnesyltransferase and geranylgeranyltransferase active site. PMID: 15451670
- Geranylgeranyltransferase inhibitor-2147 (GGTI-2147), an inhibitor of protein prenylation, elicited significant inhibition of glucose-stimulated insulin secretion from INS 832/13 islet cells. PMID: 17192483
- FTase, via its tubulin-association, is a critical upstream regulator of HDAC6 activity PMID: 19228685
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蛋白家族：Protein prenyltransferase subunit alpha family
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數據庫鏈接：
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