在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FNDC3B Antibody, Biotin conjugated

  • 中文名稱:
    FNDC3B兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào):
    CSB-PA709599LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) FNDC3B Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    FNDC3B
  • 別名:
    FNDC3B antibody; FAD104 antibody; NS5ABP37 antibody; UNQ2421/PRO4979/PRO34274Fibronectin type III domain-containing protein 3B antibody; Factor for adipocyte differentiation 104 antibody; HCV NS5A-binding protein 37 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Fibronectin type III domain-containing protein 3B protein (5-71AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    May be a positive regulator of adipogenesis.
  • 基因功能參考文獻(xiàn):
    1. we found that knockdown of FNDC3B could suppress the migratory and invasive abilities of OTSCC cells. In addition, treating OTSCC cells with CoCl2 (a hypoxia mimetic agent) upregulated the mRNA and protein expression of FNDC3B via HIF-1alpha PMID: 29393475
    2. FNDC3B and ANXA2 expression correlate negatively with patient survival in hepatocellular carcinoma PMID: 27385217
    3. we report the first two patients with de novo 3q26.31 microdeletions. Both have dysmorphic features, consistent with the phenotypes seen in fndc3b-deficient mice in animal studies, which imply a critical role of FNDC3B in human craniofacial development. PMID: 27541078
    4. findings together indicate that NS5ABP37 inhibits cancer cell proliferation and promotes apoptosis, by altering SREBP-dependent lipogenesis and cholesterogenesis in HepG2 and L02 cells and inducing oxidative stress and endoplasmic reticulum stress PMID: 27862769
    5. MiR-129-5p could directly suppress FNDC3B. PMID: 28068630
    6. fad104 suppressed anchorage-independent growth of melanoma cells, and the N-terminal region of FAD104 is essential for inhibiting malignant transformation and STAT3 activity PMID: 26948083
    7. fad104 suppressed the invasion and metastasis of melanoma cells by inhibiting activation of the STAT3 signaling pathway PMID: 25671570
    8. Central corneal thickness-associated loci FNDC3B confers a relatively large risk for keratoconus and is also associated with primary open-angle glaucoma. PMID: 23291589
    9. FNDC3B amplification is involved in tumor maintenance in addition to its ability to promote cancer. PMID: 22510613
    10. Up-regulation of miR-143 expression transcribed by NF-kappaB in hepatitis B virus-related hepatocellular carcinoma promotes cancer cell invasion/migration and tumor metastasis by repression of FNDC3B expression. PMID: 19472311

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Membrane; Single-pass membrane protein.
  • 蛋白家族:
    FNDC3 family
  • 組織特異性:
    Predominantly expressed in white adipose tissue (WAT) especially in the stromal vascular cells. Expressed in adipocyte differentiable 3T3-L1 cells but not in the non-adipogenic cell line NIH-3T3. Expression increased in the early stage of adipogenesis.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 24670

    OMIM: 611909

    KEGG: hsa:64778

    STRING: 9606.ENSP00000338523

    UniGene: Hs.744888



主站蜘蛛池模板: 精品国产污污免费网站入口| 性欧美老人牲交xxxxx视频| 热久久美女精品天天吊色| 国产精品原创巨作av女教师| 无码av片av片av无码| 在线看片免费人成视频在线影院 | 日产精品久久久久久久性色| 中文字幕在线亚洲精品| 麻豆亚洲国产成人精品无码区| 亚洲制服 视频在线观看| 又色又爽又黄还免费毛片96下载| 好大好硬好爽免费视频| 国产无遮挡裸体免费视频在线观看| 欧美性生交xxxxx久久久| 强迫大乳人妻中文字幕| 亚洲加勒比少妇无码av| 国产精品久久毛片| 成人做爰69片免费看网站| 奇米影视777四色狠狠| 一本精品99久久精品77 | 少妇又色又紧又爽又刺激视频| 在厨房拨开内裤进入毛片| 国产草莓精品国产av片国产| 亚洲va久久久噜噜噜久久无码| 欧美野性肉体狂欢大派对| 十八岁以下禁止观看黄下载链接| 18禁亚洲深夜福利人口| 色偷偷www.8888在线观看 | 欧美顶级少妇作爱| 波多野结衣绝顶大高潮| 成人免费午夜无码视频在线播放| 精品国产午夜理论片不卡精品| 国产日产久久高清欧美一区| 日本最新免费二区三区| 久久精品女人的天堂av| 久久亚洲欧美国产精品| 亚洲精品一区二三区不卡| 美女裸体色黄污视频网站| 亚洲va天堂va欧美ⅴa在线| 国产午夜理论不卡在线观看| 国产又粗又硬又大爽黄老大爷视频 |