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  4. FMRFa Antibody

FMRFa Antibody

Rare Species
  • 中文名稱：
    FMRFa兔多克隆抗體
  • 貨號：
    CSB-PA016032XA01DLU
  • 規格：
    ￥440
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    FMRFa
  • 別名：
    FMRFamide-related peptides [Cleaved into: FMRFamide A; Corticotropin-releasing factor-like; AAMDRY-amide; DPKQDFMRF-amide; TPAEDFMRF-amide; SDNFMRF-amide; SPKQDFMRF-amide; PDNFMRF-amide; SAPQDFVRS-amide; MDSNFIRF-amide] FMRFa Fmrf CG2346
  • 反應種屬：
    Drosophila melanogaster (Fruit fly)
  • 免疫原：
    Synthetic Peptide (204-208aa)
  • 免疫原種屬：
    Drosophila melanogaster (Fruit fly)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Affinity-chromatography
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    In insects, FMRFamide and related peptides have modulatory actions at skeletal neuromuscular junctions, and peptides that are immunologically related to FMRFamide are released into the circulation from neurohemal organs.
  • 基因功能參考文獻：
    1. Animals mutant for either FMRFamide or for the FMRFamide receptor (FR) have a reduced recovery sleep in response to heat stress. PMID: 25668617
    2. DPKQDFMRFamide induces contractions via a G-protein coupled FMRFamide receptor in muscle cells but does not appear to act via cAMP, cGMP, CaMKII or arachidonic acid. PMID: 24526728
    3. Klu is expressed specifically in the postmitotic Ap4/FMRFa neuron, promoting its differentiation through the initiation of BMP signaling PMID: 23633512
    4. DPKQDFMRFamide modulates both synaptic function and behavior through coincident detection mediated by FMRF receptor and dromyosuppressin receptor-2. PMID: 21048131
    5. Here, we review FMRFamide-containing peptides encoded by the D. melanogaster FMRFamide gene in order to review the data on the expression, regulation, and activity of these peptides as well as acknowledge endeavors required to elucidate FaRP signaling. PMID: 11814637
    6. Supplying FMRFa in neurosecretory cells partially rescues the wit lethal phenotype. PMID: 14507784
    7. hybridization in situ shows a lack of co-localization of mRNAs for the circadian neuropeptide PDF and FMRFamide in brains of the flies Musca domestica and Drosophila melanogaster PMID: 17426155

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  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    FARP (FMRFamide related peptide) family
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG2346

    STRING: 7227.FBpp0087471

    UniGene: Dm.7156



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