在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. FKBP6 Antibody

FKBP6 Antibody

  • 中文名稱：
    FKBP6兔多克隆抗體
  • 貨號：
    CSB-PA008702LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA008702LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA008702LA01HU at dilution of 1:100
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA008702LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Western Blot
      Positive WB detected in: HEK293 whole cell lysate
      All lanes: FKBP6 antibody at 4µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 38, 37, 34 kDa
      Observed band size: 38 kDa
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) FKBP6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    FKBP6
  • 別名：
    36 kDa FK506 binding protein antibody; 36 kDa FK506-binding protein antibody; 36 kDa FKBP antibody; EC 5.2.1.8 antibody; FK506 binding protein 6 antibody; FK506-binding protein 6 antibody; FKBP 36 antibody; FKBP-36 antibody; FKBP-6 antibody; FKBP36 antibody; fkbp6 antibody; FKBP6_HUMAN antibody; Immunophilin FKBP36 antibody; Peptidyl prolyl cis trans isomerase antibody; Peptidyl-prolyl cis-trans isomerase FKBP6 antibody; PPIase antibody; PPIase FKBP6 antibody; Rotamase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Inactive peptidyl-prolyl cis-trans isomerase FKBP6 protein (101-327AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，FKBP6 Antibody (CSB-PA008702LA01HU)，的標記方式是Non-conjugated。對于FKBP6 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA008702LB01HU FKBP6 Antibody, HRP conjugated ELISA
    FITC CSB-PA008702LC01HU FKBP6 Antibody, FITC conjugated
    Biotin CSB-PA008702LD01HU FKBP6 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.
  • 基因功能參考文獻：
    1. Genome wide DNA methylation assessment approach identified novel biomarkers that differentiate between cervical cancer and normal samples. In the Validation cohort FKBP6 promoter methylation had 73% sensitivity and 80% specificity (AUC = 0.80). PMID: 24241165
    2. 278A polymorphism of FKBP6 gene was associated with idiopathic azoospermia, while C/T, 370G/A, 430G/C, 467T/C, 468G/A polymorphisms might be very rare in Chinese population. PMID: 15696470
    3. may play a role in modifying the susceptibility to idiopathic spermatogenic impairment in human; allele A of c.216C>A seems to be a protective factor for the development of male infertility PMID: 17307919
    4. clathrin-FKBP36-Hsp72 complexes resulting from both identified interactions are bound to the matrices of clathrin-coated vesicles in spermatocytes, which indicates a possible role of FKBP36 and Hsp72 in the disassembly of clathrin coats PMID: 18529014
    5. FKBP36 diminishes GAPDH activity by direct interaction and down-regulation of GAPDH PMID: 19001379

    顯示更多

    收起更多

  • 相關疾病：
    FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease (PubMed:9782077). A father and son with Williams-Beuren syndrome appear to have a common heterozygous deletion that includes FKBP6 gene. However, the haploinsufficiency for FKBP6 does not appear to preclude male fertility (PubMed:15770126).
  • 亞細胞定位：
    Cytoplasm, cytosol. Nucleus. Chromosome.
  • 蛋白家族：
    FKBP6 family
  • 組織特異性：
    Detected in all tissues examined, with higher expression in testis, heart, skeletal muscle, liver, and kidney.
  • 數據庫鏈接：

    HGNC: 3722

    OMIM: 604839

    KEGG: hsa:8468

    STRING: 9606.ENSP00000252037

    UniGene: Hs.661266



主站蜘蛛池模板： 亚洲 日韩 国产欧美 另类| 亚洲午夜无码久久久久蜜臀av| 国产精品久久香蕉免费播放| 精品系列无码一区二区三区| 青青草在在观免费福利线观看| 肥臀熟女一区二区三区| 人人妻人人澡人人爽超污| 欧美xxxx做受欧美1314| 天天槽夜夜槽槽不停| 国产精品夜色一区二区三区| 成人欧美一区二区三区黑人| 69天堂人成无码免费视频| 久久精品国产只有精品66| 极品美女扒开粉嫩小泬| 少妇脱了内裤让我添| 国内外精品激情刺激在线| 97国产一区二区三区四区久久| 成人无码精品1区2区3区免费看| 一区二区三区在线 | 欧| 亚洲日韩小电影在线观看| 久久天天躁狠狠躁夜夜2019| 蜜臀av在线播放一区二区三区| 天天躁日日躁狠狠躁| 免费人成网站视频在线观看| 男女18禁啪啪无遮挡| 国产精品久久久久av福利动漫| 亚洲 另类 在线 欧美 制服| 亚洲国产欧美在线成人aaaa| 69sex久久精品国产麻豆| 国产香港明星裸体xxxx视频| 一区二区在线 | 国| 久久av无码精品人妻出轨| 中文字幕精品久久久乱码乱码| 秋秋影视午夜福利高清| 国产福利免费视频不卡| 亚洲成a人v影院色老汉影院| 久久久橹橹橹久久久久高清| 国产a v高清一区二区三区| 鲁鲁狠狠狠7777一区二区| 天堂а√在线中文在线| 日本中文字幕人妻不卡dvd|