在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. FICD Antibody, Biotin conjugated

FICD Antibody, Biotin conjugated

  • 中文名稱：
    FICD兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA880112LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) FICD Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    FICD
  • 別名：
    FICD; HIP13; HYPE; UNQ3041/PRO9857; Protein adenylyltransferase FICD; AMPylator FICD; De-AMPylase FICD; FIC domain-containing protein; Huntingtin yeast partner E; Huntingtin-interacting protein 13; HIP-13; Huntingtin-interacting protein E
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Adenosine monophosphate-protein transferase FICD protein (63-185AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Protein that can both mediate the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (AMPylation), and the removal of the same modification from target proteins (de-AMPylation), depending on the context. The side chain of Glu-231 determines which of the two opposing activities (AMPylase or de-AMPylase) will take place. Acts as a key regulator of the ERN1/IRE1-mediated unfolded protein response (UPR) by mediating AMPylation or de-AMPylation of HSPA5/BiP. In unstressed cells, acts as an adenylyltransferase by mediating AMPylation of HSPA5/BiP at 'Thr-518', thereby inactivating it. In response to endoplasmic reticulum stress, acts as a phosphodiesterase by mediating removal of ATP (de-AMPylation) from HSPA5/BiP at 'Thr-518', leading to restore HSPA5/BiP activity. Although it is able to AMPylate RhoA, Rac and Cdc42 Rho GTPases in vitro, Rho GTPases do not constitute physiological substrates.
  • 基因功能參考文獻：
    1. The single catalytic domain of FICD can release the attached AMP, restoring functionality to BiP. PMID: 27918543
    2. We first demonstrate efficient enrichment and fast visualization of potential HYPE substrates in cell lysates by in-gel fluorescence, followed by robust identification via shotgun proteomics on a QExactive mass spectrometer PMID: 26604261
    3. HYPE is an unfolded protein response regulator. PMID: 25601083
  • 亞細胞定位：
    Endoplasmic reticulum membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Fic family
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18416

    KEGG: hsa:11153

    STRING: 9606.ENSP00000446479

    UniGene: Hs.661891



主站蜘蛛池模板： 色视频综合无码一区二区三区| 日本久久久久久级做爰片| 亚洲熟女乱综合一区二区在线| 色拍拍欧美视频在线看| 国产日韩综合一区在线观看| 制服视频在线一区二区| 国产一区二区在线视频| 亚洲爆乳精品无码一区二区| 无码视频免费一区二区三区| 亚洲另类欧美综合在线| 免费无码成人片| 人人妻人人澡人人爽人人精品| 偷拍农村老熟妇xxxxx7视频| 偷欧洲亚洲另类图片av天堂| 日本老熟妇毛茸茸| 波多野美乳人妻hd电影欧美| 色欲天天婬色婬香综合网| 国产成人最新三级在线视频| 女邻居的大乳中文字幕| 日本中文字幕有码在线视频| 最近日本免费观看高清视频| 鲁一鲁一鲁一鲁一曰综合网| 日韩成人无码毛片一区二区| 精品福利视频一区二区三区| 色妞ww精品视频7777| 67pao国产成视频永久免费| 97se亚洲综合自在线| 亚洲中文字幕乱码电影| 男女性杂交内射女bbwxz| 40岁成熟女人牲交片20分钟| 女人国产香蕉久久精品| 女人与公拘交酡全过程| 国产在线精品一区二区在线看| 51视频国产精品一区二区| 伦伦影院午夜理论片| 国产熟妇乱xxxxx大屁股网| 狠狠做五月深爱婷婷| 人人妻人人澡人人爽欧美精品| 国产亚洲精品久久久久久入口| 在线高清理伦片a| 波多野42部无码喷潮在线|